Evidence map›Paper›PMID 19703517›Full record

ReviewMolecular and cellular endocrinology2010

Stranger in a strange land: roles of glycogen turnover in adipose tissue metabolism.

Kathleen R Markan, Michael J Jurczak, Matthew J Brady

Abstract readReview
In one paragraph

Review in Molecular and cellular endocrinology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Metabolic characteristics of human subcutaneous abdominal adipose tissue after overnight fast.American journal of physiology. Endocrinology and metabolism · 2012
    Pooled it
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  16. Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation.Laboratory investigation; a journal of technical methods and pathology · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kathleen R MarkanDepartment of Medicine, Section of Endocrinology, Diabetes and Metabolism, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA.
Michael J Jurczak
Matthew J Brady
University of Chicago · USYale University · US

Funding

ROLE OF PTG IN ADIPOCYTIC GLYCOGEN METABOLISMR01DK064772 · NIDDK · UNIVERSITY OF CHICAGO · PI BRADY, MATTHEW J · 2004 to 2012
$2.6M
NIDDK NIH HHS R01 DK064772
6 · The paper itself

Abstract

Triglyceride storage in adipose tissue comprises the principal energy reserve in mammals. Additionally glucose can be stored as glycogen in the fed state, primarily in liver and skeletal muscle, for mobilization during times of energy deficit. Adipose tissue also contains glycogen stores albeit at very low levels. The physiological role of glycogen metabolism in adipocytes remains unclear. However, both classical literature and more recent work demonstrate that the dynamic regulation of adipose glycogen may serve as an energy sensing modality in the coordination of glucose and lipid metabolism in adipose tissue, especially during the fasted to fed transition.

Indexed as

Adipose TissueAnimalsGlycogenHumansGlycogen

Identifiers

PMID19703517
PMCPMC2826604
OpenAlexW1969952356

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.