ArticlePloS one2009
Hypertensive target organ damage in Ghanaian civil servants with hypertension.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Prevalence of nephropathy among patients with diabetes mellitus in Africa: a systematic review and meta-analysis.Frontiers in clinical diabetes and healthcare · 2025Pooled it
- Prevalence and burden of chronic kidney disease among the general population and high-risk groups in Africa: a systematic review.BMJ open · 2018Pooled it
- The prevalence, awareness, and control of hypertension among workers in West Africa: a systematic review.Global health action · 2015Pooled it
- Prevalence of target organ damage in rural Kenya and The Gambia: a cross-sectional study.The Lancet regional health. Africa · 2026Article
- High Rates of Undiagnosed Target Organ Damage Among Adults with Elevated Blood Pressure or Diabetes Mellitus in a Community-Based Survey in Lesotho.Journal of epidemiology and global health · 2023Article
- Predictors of Nonadherence to Medications among Hypertensive Patients in Ghana: An Application of the Health Belief Model.International journal of hypertension · 2022Article
- Ambulatory blood pressure monitoring and management of hypertension at a cardiac clinic in Kumasi Metropolis, Ghana.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Prevalence of Hypertensive Emergency and Associated Factors Among Hospitalized Patients with Hypertensive Crisis: A Retrospective Cross-Sectional Study.Integrated blood pressure control · 2020Article
- Self-reported hypertension as a predictor of chronic health conditions among older adults in Ghana: analysis of the WHO Study on global Ageing and adult health (SAGE) Wave 2.The Pan African medical journal · 2020Article
- Hypertension in a resource-limited setting: Poor Outcomes on Short-term Follow-up in an Urban Hospital in Maputo, Mozambique.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Retinal imaging to identify target organ damage in older Africans: A pilot study.Journal of clinical hypertension (Greenwich, Conn.) · 2018Article
- Prevalence and clinical spectrum of hypertensive retinopathy among hypertension clinic patients at Queen Elizabeth Central Hospital in Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2018Article
- Microalbuminuria and Retinopathy among Hypertensive Nondiabetic Patients at a Large Public Outpatient Clinic in Southwestern Uganda.International journal of nephrology · 2018Article
- Impaired renal function in a rural Ugandan population cohort.Wellcome open research · 2018Article
- Prevalence, awareness, and associated risk factors of hypertension in older adults in Africa: a systematic review and meta-analysis protocol.Systematic reviews · 2017Article
- A Profile of Renal Function in Northern Cameroonians with Essential Hypertension.Cardiorenal medicine · 2017Article
- Serum Creatine Kinase-MB Isoenzyme Activity among Subjects with Uncomplicated Essential Hypertension: Any Sex Differences.Medical sciences (Basel, Switzerland) · 2017Article
- Overweight and obesity prevalence among public servants in Nadowli district, Ghana, and associated risk factors: a cross-sectional study.BMC obesity · 2017Article
- An Analysis of Anthropometric Indicators and Modifiable Lifestyle Parameters Associated with Hypertensive Nephropathy.International journal of hypertension · 2016Article
- Relationship between retinopathy and renal abnormalities in black hypertensive patients.Clinical hypertension · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundLow levels of detection, treatment and control of hypertension have repeatedly been reported from sub Saharan Africa, potentially increasing the likelihood of target organ damage.
methodsA cross-sectional study was conducted on 1015 urban civil servants aged > or = 25 years from seven central government ministries in Accra, Ghana. Participants diagnosed to have hypertension were examined for target organ involvement. Hypertensive target organ damage was defined as the detection of any of the following: left ventricular hypertrophy diagnosed by electrocardiogram, reduction in glomerular filtration rate, the presence of hypertensive retinopathy or a history of a stroke.
resultsOf the 219 hypertensive participants examined, 104 (47.5%) had evidence of target organ damage. The presence of target organ damage was associated with higher systolic and diastolic blood pressure levels. The odds of developing hypertensive target organ damage was five to six times higher in participants with blood pressure (BP) > or = 180/110 mmHg compared to those with BP < 140/90 mmHg, and there was a trend to higher odds of target organ damage with increasing BP (p = 0.001). Women had about lower odds of developing target organ damage compared to men.
conclusionsThe high prevalence of target organ damage in this working population associated with increasing blood pressure, emphasises the need for hypertension control programs aimed at improving the detection of hypertension, and importantly addressing the issues inhibiting the effective treatment and control of people with hypertension in the population.
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