Trial reportObstetrics and gynecology2009
Defining success after surgery for pelvic organ prolapse.
Trial report in Obstetrics and gynecology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 226 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
CARE: A Randomized Trial of Colpopexy and Urinary Reduction Efforts
Calistar A vs. Calistar S - Cohort Retrospective Analysis
Barbed Suture Versus Non-Barbed Suture for Posterior Colporrhaphy: A Randomized Controlled Trial
Effect of Local Estriol Treatment Before Vaginal Repair Surgery on Vaginal Tissues and Early Postoperative Pelvic Floor Functions
Who cites it
226 citing papers in PubMed, 6 syntheses or guidelines pooled it, 493 citations in OpenAlex.
- Abdominal and vaginal pelvic support with concomitant hysterectomy for uterovaginal pelvic prolapse: a comparative systematic review and meta-analysis.International urogynecology journal · 2021Pooled it
- The impact of surgical simulation on patient outcomes: a systematic review and meta-analysis.Neurosurgical review · 2021Pooled it
- A systematic review of the psychometric properties of the cross-cultural adaptations and translations of the Prolapse Quality of Life (P-QoL) questionnaire.International urogynecology journal · 2019Pooled it
- Systematic review of definitions for success in pelvic organ prolapse surgery.International urogynecology journal · 2018Pooled it
- The treatment of post-hysterectomy vaginal vault prolapse: a systematic review and meta-analysis.International urogynecology journal · 2017Pooled it
- Pooled it
- Outcomes by frailty and mobility in older patients undergoing major urogynecologic surgery: a planned supplementary study of the apical suspension repair for vault prolapse in a three-arm randomized (ASPIRe) trial.American journal of obstetrics and gynecology · 2026Trial
- Activity Restrictions After Midurethral Sling: A Randomized Controlled Trial.Urogynecology (Philadelphia, Pa.) · 2026Trial
- Defining success after surgical treatment of stress urinary incontinence.American journal of obstetrics and gynecology · 2024Trial
- Efficacy of Sacrospinous Fixation or Uterosacral Ligament Suspension for Pelvic Organ Prolapse in Stages III and IV: Randomized Clinical Trial.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023Trial
- Five-year surgical outcomes of transvaginal apical approaches in women with advanced pelvic organ prolapse.International urogynecology journal · 2023Trial
- Trial
- Characteristics associated with subjective and objective measures of treatment success in women undergoing percutaneous tibial nerve stimulation vs sham for accidental bowel leakage.International urogynecology journal · 2023Trial
- Subjective outcomes 12 years after transvaginal mesh versus native tissue repair in women with recurrent pelvic organ prolapse; a randomized controlled trial.International urogynecology journal · 2023Trial
- Fast track sacrospinous ligament fixation: subjective and objective outcomes at 6 months.BMC women's health · 2021Trial
- Outcomes of native tissue transvaginal apical approaches in women with advanced pelvic organ prolapse and stress urinary incontinence.International urogynecology journal · 2020Trial
- Long-term outcomes of a randomized controlled trial comparing trans-obturator vaginal mesh with native tissue repair in the treatment of anterior vaginal wall prolapse.International urogynecology journal · 2020Trial
- Surgical interventions for uterine prolapse and for vault prolapse: the two VUE RCTs.Health technology assessment (Winchester, England) · 2020Trial
- Long-term outcome of vaginal mesh or native tissue in recurrent prolapse: a randomized controlled trial.International urogynecology journal · 2018Trial
- Trial
166 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesTo describe pelvic organ prolapse surgical success rates using a variety of definitions with differing requirements for anatomic, symptomatic, or re-treatment outcomes.
methodsEighteen different surgical success definitions were evaluated in participants who underwent abdominal sacrocolpopexy within the Colpopexy and Urinary Reduction Efforts trial. The participants' assessments of overall improvement and rating of treatment success were compared between surgical success and failure for each of the definitions studied. The Wilcoxon rank sum test was used to identify significant differences in outcomes between success and failure.
resultsTreatment success varied widely depending on definition used (19.2-97.2%). Approximately 71% of the participants considered their surgery "very successful," and 85.2% considered themselves "much better" than before surgery. Definitions of success requiring all anatomic support to be proximal to the hymen had the lowest treatment success (19.2-57.6%). Approximately 94% achieved surgical success when it was defined as the absence of prolapse beyond the hymen. Subjective cure (absence of bulge symptoms) occurred in 92.1% while absence of re-treatment occurred in 97.2% of participants. Subjective cure was associated with significant improvements in the patient's assessment of both treatment success and overall improvement, more so than any other definition considered (P<.001 and <.001, respectively). Similarly, the greatest difference in symptom burden and health-related quality of life as measured by the Pelvic Organ Prolapse Distress Inventory and Pelvic Organ Prolapse Impact Questionnaire scores between treatment successes and failures was noted when success was defined as subjective cure (P<.001).
conclusionThe definition of success substantially affects treatment success rates after pelvic organ prolapse surgery. The absence of vaginal bulge symptoms postoperatively has a significant relationship with a patient's assessment of overall improvement, while anatomic success alone does not. LEVEL OF EVIDENCE: II.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.