ArticleAmerican journal of epidemiology2009
Pesticides and myocardial infarction incidence and mortality among male pesticide applicators in the Agricultural Health Study.
Article in American journal of epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterization.Expert opinion on drug metabolism & toxicology · 2021Pooled it
- Residential proximity to agricultural pesticide use and cardiovascular disease risk factors among adult Latina women in California's Salinas Valley.American journal of epidemiology · 2024Article
- Informing Hazard Identification and Risk Characterization of Environmental Chemicals by Combining Transcriptomic and Functional Data from Human-Induced Pluripotent Stem-Cell-Derived Cardiomyocytes.Chemical research in toxicology · 2024Article
- Review
- An ecological study regarding the association between paraquat exposure and end stage renal disease.Environmental health : a global access science source · 2022Article
- Synergistic action of organophosphates and COVID-19 on inflammation, oxidative stress, and renin-angiotensin system can amplify the risk of cardiovascular maladies.Toxicology and applied pharmacology · 2022Article
- Use of permethrin and other pyrethroids and mortality in the Agricultural Health Study.Occupational and environmental medicine · 2022Article
- Social and environmental risks as contributors to the clinical course of heart failure.Heart failure reviews · 2022Review
- Cardiotoxicity of some pesticides and their amelioration.Environmental science and pollution research international · 2021Review
- Inhalation of publicly available indoor insecticide spray caused myocardial infarction type II: a case report.ESC heart failure · 2021Article
- Case Report: Effective Treatment for Acute Chlorpyrifos Poisoning Complicated by a Non-ST-Segment Elevation Myocardial Infarction.Frontiers in cardiovascular medicine · 2021Article
- Occupational Exposures and Cardiac Structure and Function: ECHO-SOL (Echocardiographic Study of Latinos).Journal of the American Heart Association · 2020Observational
- Association between intake of fruits and vegetables by pesticide residue status and coronary heart disease risk.Environment international · 2019Article
- Overall and cause-specific mortality in a cohort of farmers and their spouses.Occupational and environmental medicine · 2019Article
- Exposure to Agrochemicals and Cardiovascular Disease: A Review.International journal of environmental research and public health · 2016Review
- Khat use: history and heart failure.Oman medical journal · 2015Review
- Overview of the National Occupational Mortality Surveillance (NOMS) system: leukemia and acute myocardial infarction risk by industry and occupation in 30 US states 1985-1999, 2003-2004, and 2007.American journal of industrial medicine · 2015Article
- The Long-Term Effects of Organophosphates Poisoning as a Risk Factor of CVDs: A Nationwide Population-Based Cohort Study.PloS one · 2015Article
- Agricultural exposures and stroke mortality in the Agricultural Health Study.Journal of toxicology and environmental health. Part A · 2013Article
- Pesticide use and myocardial infarction incidence among farm women in the agricultural health study.Journal of occupational and environmental medicine · 2010Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Acute organophosphate and carbamate pesticide poisonings result in adverse cardiac outcomes. The cardiac effects of chronic low-level pesticide exposure have not been studied. The authors analyzed self-reported lifetime use of pesticides reported at enrollment (1993-1997) and myocardial infarction mortality through 2006 and self-reported nonfatal myocardial infarction through 2003 among male pesticide applicators in the Agricultural Health Study. Using proportional hazard models, the authors estimated the association between lifetime use of 49 pesticides and fatal and nonfatal myocardial infarction. There were 476 deaths from myocardial infarction among 54,069 men enrolled in the study and 839 nonfatal myocardial infarctions among the 32,024 participants who completed the follow-up interview. Fatal and nonfatal myocardial infarctions were associated with commonly reported risk factors, including age and smoking. There was little evidence of an association between having used pesticides, individually or by class, and myocardial infarction mortality (e.g., insecticide hazard ratio (HR) = 0.91, 95% confidence interval (CI): 0.67, 1.24; herbicide HR = 0.74, 95% CI: 0.49, 1.10) or nonfatal myocardial infarction incidence (e.g., insecticide HR = 0.85, 95% CI: 0.66, 1.09; herbicide HR = 0.91, 95% CI: 0.61, 1.36). There was no evidence of a dose response with any pesticide measure. In a population with low risk for myocardial infarction, the authors observed little evidence of increased risk of myocardial infarction mortality or nonfatal myocardial infarction associated with the occupational use of pesticides.
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