Evidence map›Paper›PMID 19700031›Full record

ReviewNutrition research (New York, N.Y.)2009

Green tea and bone metabolism.

Chwan-Li Shen, James K Yeh, Jay J Cao, Jia-Sheng Wang

Erratum issued Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Nutrition research (New York, N.Y.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT00625391 (GTP and Tai Chi for Bone Health), which is not on this map. Cited by 69 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 4 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00625391 phase1 / phase2completednot on this map

GTP and Tai Chi for Bone Health: a Pilot Study

TypeinterventionalSponsorTexas Tech University Health Sciences CenterRan2008 to 2009Enrolled171ConditionsOsteoporosisArmsPlacebo, Green Tea Polyphenols (GTP), Placebo+Tai Chi (TC), GTP+TC
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 177 citations in OpenAlex.

  1. Pooled it
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  19. Journal of materials chemistry. B · 2023
    Article
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Chwan-Li ShenDepartment of Pathology, Texas Tech University Health Sciences Center, Lubbock, TX 79430-9097, USA. leslie.shen@ttuhsc.edu
James K Yeh
Jay J Cao
Jia-Sheng Wang
Grand Forks Human Nutrition Research Center · USTexas Tech University · USUniversity of Georgia · USWinthrop-University Hospital · US

Funding

Chemoprevention of Green Tea Polyphenol on Liver CancerR01CA090997 · NCI · UNIVERSITY OF GEORGIA · PI WANG, JIA-SHENG · 2003 to 2007
$1.8M
GTP and Tai Chi for Bone Health: a Pilot StudyR21AT003735 · NCCIH · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI SHEN, CHWAN-LI L · 2007 to 2008
$568k
NCCIH NIH HHS R21 AT003735NCCIH NIH HHS R21AT003735NCI NIH HHS CA90997NCI NIH HHS R01 CA090997
6 · The paper itself

Abstract

Osteoporosis is a major health problem in both elderly women and men. Epidemiological evidence has shown an association between tea consumption and the prevention of age-related bone loss in elderly women and men. Ingestion of green tea and green tea bioactive compounds may be beneficial in mitigating bone loss of this population and decreasing their risk of osteoporotic fractures. This review describes the effect of green tea or its bioactive components on bone health, with an emphasis on (i) the prevalence and etiology of osteoporosis; (ii) the role of oxidative stress and antioxidants in osteoporosis; (iii) green tea composition and bioavailability; (iv) the effects of green tea and its active components on osteogenesis, osteoblastogenesis, and osteoclastogenesis from human epidemiological, animal, as well as cell culture studies; (v) possible mechanisms explaining the osteoprotective effects of green tea bioactive compounds; (vi) other bioactive components in tea that benefit bone health; and (vii) a summary and future direction of green tea and bone health research and the translational aspects. In general, tea and its bioactive components might decrease the risk of fracture by improving bone mineral density and supporting osteoblastic activities while suppressing osteoclastic activities.

Indexed as

TeaAgedAntioxidantsBone DensityBone Density Conservation AgentsBone RemodelingCamellia sinensisFemaleFractures, BoneHumansMaleOsteoporosisPhytotherapyPlant ExtractsAntioxidantsBone Density Conservation AgentsPlant ExtractsTea

Identifiers

PMID19700031
PMCPMC2754215
OpenAlexW2109934063

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.