ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2009
Outcome of critically ill patients with influenza virus infection.
Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Article
- Optimization of an Inclusion Body-Based Production of the Influenza Virus Neuraminidase inBiomolecules · 2022Article
- Risk Factors Associated with 30-Day Mortality in Older Patients with Influenza.Journal of clinical medicine · 2021Article
- Clinical Characteristics and Predictors of Mortality in Critically Ill Influenza Adult Patients.Journal of clinical medicine · 2020Article
- Molecular point-of-care testing for respiratory viruses versus routine clinical care in adults with acute respiratory illness presenting to secondary care: a pragmatic randomised controlled trial protocol (ResPOC).BMC infectious diseases · 2017Article
- Risk Factors for Influenza-Associated Severe Acute Respiratory Illness Hospitalization in South Africa, 2012-2015.Open forum infectious diseases · 2017Article
- Lethal H1N1 influenza A virus infection alters the murine alveolar type II cell surfactant lipidome.American journal of physiology. Lung cellular and molecular physiology · 2016Article
- Point-of-care testing for respiratory viruses in adults: The current landscape and future potential.The Journal of infection · 2015Review
- TGF-β-induced IL-6 prevents development of acute lung injury in influenza A virus-infected F508del CFTR-heterozygous mice.American journal of physiology. Lung cellular and molecular physiology · 2015Article
- Pathogenic influenza B virus in the ferret model establishes lower respiratory tract infection.The Journal of general virology · 2014Article
- Influenza in pregnancy.Influenza and other respiratory viruses · 2013Review
- Influenza A H1N1 induces declines in alveolar gas exchange in mice consistent with rapid post-infection progression from acute lung injury to ARDS.Influenza and other respiratory viruses · 2013Article
- Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.PLoS pathogens · 2013Article
- Article
- Intensive care unit patients with 2009 pandemic influenza A (H1N1pdm09) virus infection - United States, 2009.Influenza and other respiratory viruses · 2012Article
- Postinfection A77-1726 treatment improves cardiopulmonary function in H1N1 influenza-infected mice.American journal of respiratory cell and molecular biology · 2012Article
- Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice.G3 (Bethesda, Md.) · 2012Article
- Clinical features, complications and mortality in critically ill patients with 2009 influenza A(H1N1) in Sfax,Tunisia.Influenza and other respiratory viruses · 2011Article
- Acute respiratory distress syndrome caused by influenza B virus infection in a patient with diffuse large B-cell lymphoma.Case reports in medicine · 2011Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfluenza is a major cause of morbidity and mortality, with its greatest burden on the elderly and patients with chronic co-morbidities in the intensive care unit (ICU). An accurate prognosis is essential for decision-making during pandemic as well as interpandemic periods.
methodsA retrospective cohort study was conducted to determine prognostic factors influencing short term outcome of critically ill patients with confirmed influenza virus infection. Baseline characteristics, laboratory and diagnostic findings, ICU interventions and complications were abstracted from medical records using standard definitions and compared between hospital survivors and non-survivors with univariate and multivariate logistic regression analyses.
results111 patients met the inclusion criteria. Acute respiratory distress syndrome (ARDS) complicated ICU course in 25 (23%) of the patients, with mortality rate of 52%. Multivariate logistic regression analysis identified the following predictors of hospital mortality: Acute Physiology and Chronic Health Evaluation (APACHE) III predicted mortality (Odds ratio [OR] 1.49, 95% confidence interval [CI] 1.1-2.1 for 10% increase), ARDS (OR 7.7, 95% CI 2.3-29) and history of immunosuppression (OR 7.19, 95% CI 1.9-28).
conclusionsAPACHE III predicted mortality, the development of ARDS and the history of immunosuppression are independent risk factors for hospital mortality in critically ill patients with confirmed influenza virus infection.
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