Evidence map›Paper›PMID 19698077›Full record

ArticleThe Journal of infectious diseases2009

Antibody responses in oral fluid after administration of prophylactic human papillomavirus vaccines.

Ali Rowhani-Rahbar, Joseph J Carter, Stephen E Hawes, James P Hughes, Noel S Weiss, Denise A Galloway, Laura A Koutsky

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in The Journal of infectious diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

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  14. Emerging human papillomavirus vaccines.Expert opinion on emerging drugs · 2012
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ali Rowhani-RahbarDepartment of Epidemiology, University of Washington, Seattle, WA 98125, USA. rowhani@u.washington.edu
Joseph J Carter
Stephen E Hawes
James P Hughes
Noel S Weiss
Denise A Galloway
Laura A Koutsky
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZAUniversity of Washington · US

Funding

ACQUISITION &NATURAL HISTORY OF GENITAL HPV INFECTIONSR01AI038383 · NIAID · UNIVERSITY OF WASHINGTON · PI KOUTSKY, LAURA A · 1995 to 2009
$6.0M
HPV CAPSID ANTIBODIESR01AI038382 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GALLOWAY, DENISE A. · 1995 to 2020
$4.4M
NIAID NIH HHS R01 AI038382NIAID NIH HHS R01 AI038383NIAID NIH HHS R01-AI38383
6 · The paper itself

Abstract

We sought to determine whether oral fluid can be used to assess serum human papillomavirus (HPV) antibody status by enrolling women who had received a prophylactic HPV-16 vaccine in a new follow-up study. After the prophylactic HPV-6/11/16/18 vaccine was licensed in the United States, we administered it to consenting participants. With serologic findings used as the reference standard, The sensitivity of oral fluid was 49.6% (95% confidence interval [CI], 42.0%-57.3%) before and 100% (95% CI, 92.0%-100%) after administration of the quadrivalent vaccine. Oral fluid may have the potential to be used for monitoring of prophylactic HPV vaccines in the future.

Indexed as

AdultAntibodies, ViralExudates and TransudatesFemaleHuman papillomavirus 16Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18HumansImmunization, SecondaryImmunoglobulin GMouth MucosaPapillomavirus VaccinesRandomized Controlled Trials as TopicROC CurveAntibodies, ViralHuman Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18Immunoglobulin GPapillomavirus Vaccines

Identifiers

PMID19698077
PMCPMC3392559
OpenAlexW2074126686

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.