ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
Genotype-phenotype correlation in 9 patients with tropical pancreatitis and identified gene mutations.
Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Common calcium-sensing receptor (CASR) gene variants do not modify risk for chronic pancreatitis in a Hungarian cohort.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2021Article
- Changing phenotype and disease behaviour of chronic pancreatitis in India: evidence for gene-environment interactions.Global health, epidemiology and genomics · 2016Review
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4 authors at 1 institution in 1 country.
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Abstract
The etiopathogenesis of tropical chronic pancreatitis (TCP) remains unclear. Malnutrition, dietary toxins like cyanogens in cassava and micronutrient deficiency are proposed factors. The description and characterization of genetic factors in TCP has added a new dimension to the understanding of pathogenesis of the disease. However, there is sparse data on the association of TCP with cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations. We report 8 patients of TCP with CFTR gene mutations, including one with a novel mutation, and describe the clinical profile of these patients. Further prospective genetic studies on the association of CFTR gene mutations are essential in order to unravel the genetic basis of TCP.
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