ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2010
Femur ultrasound (FemUS)--first clinical results on hip fracture discrimination and estimation of femoral BMD.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 58 citations in OpenAlex.
- Pulse-Echo Measurements of Bone Tissues. Techniques and Clinical Results at the Spine and Femur.Advances in experimental medicine and biology · 2022Review
- Clinical Devices for Bone Assessment.Advances in experimental medicine and biology · 2022Review
- The feasibility study of the transmission mode photoacoustic measurement of human calcaneus bonePhotoacoustics · 2021Article
- Evaluation of Structural Anisotropy in a Porous Titanium Medium Mimicking Trabecular Bone Structure Using Mode-Converted Ultrasonic Scattering.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2020Article
- Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2020Review
- A Combined Ultrasonic Backscatter Parameter for Bone Status Evaluation in Neonates.Computational and mathematical methods in medicine · 2020Article
- Radiofrequency echographic multispectrometry compared with dual X-ray absorptiometry for osteoporosis diagnosis on lumbar spine and femoral neck.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Observational
- Microstructural characterization of trabecular bone using ultrasonic backscattering and diffusion parameters.The Journal of the Acoustical Society of America · 2017Article
- Ultrasound to assess bone quality.Current osteoporosis reports · 2014Article
- Discontinuation of leisure time impact-loading exercise is related to reduction of a calcaneus quantitative ultrasound parameter in young adult Japanese females: a 3-year follow-up study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014Article
- Screening and early diagnosis of osteoporosis through X-ray and ultrasound based techniques.World journal of radiology · 2013Review
- Multi-site bone ultrasound measurements in elderly women with and without previous hip fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012Article
- Can Hip Fracture Prediction in Women be Estimated beyond Bone Mineral Density Measurement Alone?Therapeutic advances in musculoskeletal disease · 2010Article
- New perspectives in echographic diagnosis of osteoporosis on hip and spine.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal DiseasesReview
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Authors and funding
11 authors at 5 institutions in 3 countries.
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No grant is acknowledged in the PubMed record.
Abstract
summaryA quantitative ultrasound (QUS) device for measurements at the proximal femur was developed and tested in vivo (Femur Ultrasound Scanner, FemUS). Hip fracture discrimination was as good as for DXA, and a high correlation with hip BMD was achieved. Our results show promise for enhanced QUS-based assessment of osteoporosis.
introductionDual X-ray absorptiometry (DXA) at the femur is the best predictor of hip fractures, better than DXA measurements at other sites. Calcaneal quantitative ultrasound (QUS) can be used to estimate the general osteoporotic fracture risk, but no femoral QUS measurement has been introduced yet. We developed a QUS scanner for measurements at the femur (Femur Ultrasound Scanner, FemUS) and tested its in vivo performance.
methodsUsing the FemUS device, we obtained femoral QUS and DXA on 32 women with recent hip fractures and 30 controls. Fracture discrimination and the correlation with femur bone mineral density (BMD) were assessed.
resultsHip fracture discrimination using the FemUS device was at least as good as with hip DXA and calcaneal QUS. Significant correlations with total hip bone mineral density were found with a correlation coefficient R (2) up to 0.72 and a residual error of about one half of a T-score in BMD.
conclusionsQUS measurements at the proximal femur are feasible and show a good performance for hip fracture discrimination. Given the promising results, this laboratory prototype should be reengineered to a clinical applicable instrument. Our results show promise for further enhancement of QUS-based assessment of osteoporosis.
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