ArticleBiomicrofluidics2007
Rapid bioparticle concentration and detection by combining a discharge driven vortex with surface enhanced Raman scattering.
Article in Biomicrofluidics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Constrained Volume Micro- and Nanoparticle Collection Methods in Microfluidic Systems.Micromachines · 2024Review
- Nanogap traps for passive bacteria concentration and single-point confocal Raman spectroscopy.Biomicrofluidics · 2023Article
- Application of Microfluidics for Bacterial Identification.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Detection and Characterization of Antibiotic-Resistant Bacteria Using Surface-Enhanced Raman Spectroscopy.Nanomaterials (Basel, Switzerland) · 2018Review
- An impedimetric bioaffinity sensing chip integrated with the long-range DC-biased AC electrokinetic centripetal vortex produced in a high conductivity solution.Biomicrofluidics · 2018Article
- Virtual vortex gear: Unique flow patterns driven by microfluidic inertia leading to pinpoint injection.Biomicrofluidics · 2018Article
- Surface enhanced Raman scattering (SERS) based biomicrofluidics systems for trace protein analysis.Biomicrofluidics · 2018Review
- Amplitude modulation schemes for enhancing acoustically-driven microcentrifugation and micromixing.Biomicrofluidics · 2016Article
- Future microfluidic and nanofluidic modular platforms for nucleic acid liquid biopsy in precision medicine.Biomicrofluidics · 2016Review
- Accelerated detection of viral particles by combining AC electric field effects and micro-Raman spectroscopy.Sensors (Basel, Switzerland) · 2015Article
- Hydrodynamic mechanisms of cell and particle trapping in microfluidics.Biomicrofluidics · 2013Review
- Optimization of microfluidic microsphere-trap arrays.Biomicrofluidics · 2013Article
- Bacterial aggregation and biofilm formation in a vortical flow.Biomicrofluidics · 2012Article
- Microfluidic concentration of bacteria by on-chip electrophoresis.Biomicrofluidics · 2011Article
- On-chip collection of particles and cells by AC electroosmotic pumping and dielectrophoresis using asymmetric microelectrodes.Biomicrofluidics · 2011Article
- Integrated electrical concentration and lysis of cells in a microfluidic chip.Biomicrofluidics · 2010Article
- A dielectrophoretic chip with a roughened metal surface for on-chip surface-enhanced Raman scattering analysis of bacteria.Biomicrofluidics · 2010Article
- Dielectrophoretic choking phenomenon in a converging-diverging microchannel.Biomicrofluidics · 2010Article
- Dynamic superconcentration at critical-point double-layer gates of conducting nanoporous granules due to asymmetric tangential fluxes.Biomicrofluidics · 2008Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid concentration and detection of bacteria in integrated chips and microfluidic devices is needed for the advancement of lab-on-a-chip devices because current detection methods require high concentrations of bacteria which render them impractical. We present a new chip-scale rapid bacteria concentration technique combined with surface-enhanced Raman scattering (SERS) to enhance the detection of low bacteria count samples. This concentration technique relies on convection by a long-range converging vortex to concentrate the bacteria into a packed mound of 200 mum in diameter within 15 min. Concentration of bioparticle samples as low as 10(4) colony forming units (CFU)ml are presented using batch volumes as large as 150 mul. Mixtures of silver nanoparticles with Saccharomyces cerevisiae, Escherichia coli F-amp, and Bacillus subtilis produce distinct and noticeably different Raman spectra, illustrating that this technique can be used as a detection and identification tool.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.