Evidence map›Paper›PMID 19692991›Full record

ArticleNature immunology2009

The sickness unto Deaf.

James M Gardner, Mark S Anderson

Open access · greenAbstract readNews
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

James M Gardner
Mark S Anderson
University of California, San Francisco · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007618 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANDERSON, MARK S · 1985 to 2020
$29.6M
Src tyrosine kinases and autoimmunity.P01AI035297 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BLUESTONE, JEFFREY A · 1993 to 2010
$16.5M
Aire-defieciency as a novel model of uveitisR01EY016408 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANDERSON, MARK S · 2005 to 2013
$3.5M
NEI NIH HHS R01 EY016408NIAID NIH HHS P01 AI035297NIGMS NIH HHS T32 GM007618
6 · The paper itself

Abstract

While promiscuous expression of tissue-specific antigens (TSAs) in the thymus is essential for self-tolerance, immunologically relevant TSA expression may also occur in the secondary lymphoid organs. A new study links the transcriptional regulator Deaf1 with altered TSA expression in the secondary lymphoid organs and autoimmune diabetes.

Indexed as

AIRE ProteinAnimalsCD8-Positive T-LymphocytesDiabetes Mellitus, Type 1DNA-Binding ProteinsLymph NodesMiceMice, Inbred NODNuclear ProteinsPancreasSelf ToleranceTranscription FactorsAIRE ProteinDEAF1 protein, humanDNA-Binding ProteinsNuclear ProteinsTranscription Factors

Identifiers

PMID19692991
PMCPMC2773699
OpenAlexW1996382431

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.