ArticleDigestive diseases and sciences2010
Heartburn and regurgitation in pregnancy: the effect of fat ingestion.
Article in Digestive diseases and sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Heartburn, Nausea, and Vomiting During Pregnancy.The American journal of gastroenterology · 2022Article
- Quality of Life During Pregnancy from 2011 to 2021: Systematic Review.International journal of women's health · 2022Review
- Lifestyle measures in the management of gastro-oesophageal reflux disease: clinical and pathophysiological considerations.Therapeutic advances in chronic disease · 2015Review
- Assessment of the Safety and Efficacy of a Raft-Forming Alginate Reflux Suppressant (Liquid Gaviscon) for the Treatment of Heartburn during Pregnancy.ISRN obstetrics and gynecology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReflux symptoms are common in pregnancy, but their association with fat ingestion is unclear.
aimTo investigate an association of dietary fats with heartburn and regurgitation in pregnancy.
methodsThis is a prospective study in which 89 pregnant women (gestational age 34 +/- 4 weeks) attending a low-risk prenatal outpatient clinic were asked to provide information on the frequency they experienced heartburn and regurgitation. Fat ingestion was estimated by means of a 24-h diet record. Symptomatic patients were compared with those with no reflux symptoms (n = 20).
resultsHeartburn once a week or more often occurred in 56 of the 89 patients (63%). The ingested amount of polyunsaturated fatty acids was higher in patients with heartburn (11.2 +/- 6.4 vs. 7.7 +/- 3.5 mg; P = 0.022) than in controls after adjusting for age, gain weight during pregnancy, ingestion of caffeine and vitamin C, and total energetic intake. The ingestion of monounsaturated fatty acids was higher in patients with heartburn, but with a borderline statistical significance (16.1 +/- 11 vs. 11.8 +/- 6.5 mg; P = 0.061). No association was observed between the consumption of fats and regurgitation.
conclusionsThis study suggests that heartburn in the third trimester of pregnancy is associated with the ingestion of polyunsaturated fatty acids.
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