ArticleRheumatology international2010
Single-nucleotide polymorphisms and expression of IL23R in Chinese ankylosing spondylitis patients.
Article in Rheumatology international, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: an updated meta-analysis.Zeitschrift fur Rheumatologie · 2019Pooled it
- Interleukin-23R rs7517847 T/G Polymorphism Contributes to the Risk of Crohn's Disease in Caucasians: A Meta-Analysis.Journal of immunology research · 2015Pooled it
- Toll-like receptor polymorphisms and rheumatoid arthritis: a systematic review.Rheumatology international · 2014Pooled it
- Interleukin-23 receptor genetic polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis.Rheumatology international · 2012Pooled it
- Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2012Pooled it
- Determination of IL-23 receptor expression and gene polymorphism (rs1884444) in Iranian patients with ankylosing spondylitis.BMC rheumatology · 2024Article
- A functional microRNA binding site variant in IL-23R gene in systemic lupus erythematosus and rheumatoid arthritis: is there any correlation?Molecular biology reports · 2022Article
- The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies.Annals of the rheumatic diseases · 2019Review
- Association of rs11209032 and rs1004819 Polymorphisms in Interleukin-23 Receptor Gene With Ankylosing Spondylitis.Archives of rheumatology · 2016Article
- Article
- Effects ofBiomedical reports · 2014Article
- Difference of interleukin-23 receptor gene haplotype variants in ulcerative colitis compared to Crohn's disease and psoriasis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2013Article
- Immunogenetic study in Chinese population with ankylosing spondylitis: are there specific genes recently disclosed?Clinical & developmental immunology · 2013Review
- Marked diversity of IL23R gene haplotype variants in rheumatoid arthritis comparing with Crohn's disease and ankylosing spondylitis.Molecular biology reports · 2013Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate the association of single-nucleotide polymorphisms (SNPs) in IL23R with ankylosing spondylitis (AS) in Chinese Han population. Six SNPs were selected for analysis in AS patients and controls. The IL23R mRNA expression was detected using RT-PCR. The differences in the genotypes of rs11209032 and the differences in the genotypes and allele frequencies of rs6677188 between cases and controls were significant. The two SNPs rs11209032 and rs6677188 were in strong linkage disequilibrium. Haplotype analysis noted a higher proportion of GAC in cases and a higher proportion of GTC in controls. The patients with AS showed an elevated level of IL23R mRNA in PBMCs. This study suggested that IL23R polymorphisms were associated with susceptibility to AS in the Chinese population and that IL23R may be involved in the development of AS.
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