ArticleJournal of experimental botany2009
A single gene, AIN, in Medicago truncatula mediates a hypersensitive response to both bluegreen aphid and pea aphid, but confers resistance only to bluegreen aphid.
Article in Journal of experimental botany, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 76 citations in OpenAlex.
- Two atypical resistance proteins confer plant resistance to Melanaphis sorghi in sorghum.Plant communications · 2026Article
- Elucidation of genetic architecture for aphid resistance in alfalfa (Medicago sativa) via genome-wide association study.BMC plant biology · 2025Article
- Ancient pangenomic origins of noncanonical NLR genes underlying the recent evolutionary rescue of a staple crop.Science advances · 2025Article
- A Nucleotide-Binding Domain Leucine-Rich Repeat Gene Regulates Plant Growth and Defense Against Chewing Herbivores.Plants (Basel, Switzerland) · 2024Article
- A Transcriptome Analysis ofInsects · 2024Article
- Genomic architecture of resistance to latania scale (H. lataniae) in kiwifruit (A. chinensis var. chinensis).BMC plant biology · 2023Article
- Article
- Research Progress and Prospect of Alfalfa Resistance to Pathogens and Pests.Plants (Basel, Switzerland) · 2022Review
- Identification and Characterization of Resistance of Three Aphid Species on Contrasting Alfalfa Cultivars.Insects · 2022Article
- Investigation of Metabolic Resistance to Soybean Aphid (Insects · 2022Article
- A functional genomics approach to dissect spotted alfalfa aphid resistance in Medicago truncatula.Scientific reports · 2020Article
- Ethylene Is Not Essential for R-Gene Mediated Resistance but Negatively Regulates Moderate Resistance to Some Aphids inInternational journal of molecular sciences · 2020Article
- An RNAi supplemented diet as a reverse genetics tool to control bluegreen aphid, a major pest of legumes.Scientific reports · 2020Article
- Additive and epistatic interactions between AKR and AIN loci conferring bluegreen aphid resistance and hypersensitivity in Medicago truncatula.Journal of experimental botany · 2019Article
- Influence of Abscisic Acid-Biosynthesis Inhibitor Fluridone on the Feeding Behavior and Fecundity ofInsects · 2019Article
- How plants handle multiple stresses: hormonal interactions underlying responses to abiotic stress and insect herbivory.Plant molecular biology · 2016Review
- Genetic Mapping of a Major Resistance Gene to Pea Aphid (Acyrthosipon pisum) in the Model Legume Medicago truncatula.International journal of molecular sciences · 2016Article
- Article
- Enhanced aphid detoxification when confronted by a host with elevated ROS production.Plant signaling & behavior · 2015Article
- Spider mites suppress tomato defenses downstream of jasmonate and salicylate independently of hormonal crosstalk.The New phytologist · 2015Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biotic stress in plants frequently induces a hypersensitive response (HR). This distinctive reaction has been studied intensively in several pathosystems and has shed light on the biology of defence signalling. Compared with microbial pathogens, relatively little is known about the role of the HR in defence against insects. Reference genotype A17 of Medicago truncatula Gaertn., a model legume, responds to aphids of the genus Acyrthosiphon with necrotic lesions resembling a HR. In this study, the biochemical nature of this response, its mode of inheritance, and its relationship with defence against aphids were investigated. The necrotic lesion phenotype and resistance to the bluegreen aphid (BGA, Acyrthosiphon kondoi Shinji) and the pea aphid (PA, Acyrthosiphon pisum (Harris)) were analysed using reference genotypes A17 and A20, their F(2) progeny and recombinant inbred lines. BGA-induced necrotic lesions co-localized with the production of H(2)O(2), consistent with an oxidative burst widely associated with hypersensitivity. This HR correlated with stronger resistance to BGA in A17 than in A20; these phenotypes cosegregated as a semi-dominant gene, AIN (Acyrthosiphon-induced necrosis). In contrast to BGA, stronger resistance to PA in A17, compared with A20, did not cosegregate with a PA-induced HR. The AIN locus resides in a cluster of sequences predicted to encode the CC-NBS-LRR subfamily of resistance proteins. AIN-mediated resistance presents a novel opportunity to use a model plant and model aphid to study the role of the HR in defence responses to phloem-feeding insects.
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