ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2009
The added value of longitudinal black-blood cardiovascular magnetic resonance angiography in the cross sectional identification of carotid atherosclerotic ulceration.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Diagnostics Accuracy of Magnetic Resonance Imaging in Detection of Atherosclerotic Plaque Characteristics in Carotid Arteries Compared to Histology: A Systematic Review.Journal of magnetic resonance imaging : JMRI · 2025Pooled it
- Intraplaque Hemorrhage and the Plaque Surface in Carotid Atherosclerosis: The Plaque At RISK Study (PARISK).AJNR. American journal of neuroradiology · 2015Trial
- Novel Imaging-Based Biomarkers for Identifying Carotid Plaque Vulnerability.Biomolecules · 2023Review
- Magnetic resonance imaging of carotid plaques: current status and clinical perspectives.Annals of translational medicine · 2020Review
- Irregular surface of carotid atherosclerotic plaque is associated with ischemic stroke: a magnetic resonance imaging study.Journal of geriatric cardiology : JGC · 2019Article
- Imaging the carotid atherosclerotic plaque.Vascular biology (Bristol, England) · 2019Review
- Association of Age and Size of Carotid Artery Intraplaque Hemorrhage and Minor Fibrous Cap Disruption: A High Resolution Magnetic Resonance Imaging Study.Journal of atherosclerosis and thrombosis · 2018Article
- Imaging of the ulcerated carotid atherosclerotic plaque: a review of the literature.Insights into imaging · 2017Review
- Repeatability of in vivo quantification of atherosclerotic carotid artery plaque components by supervised multispectral classification.Magma (New York, N.Y.) · 2015Article
- Advances in MRI for the evaluation of carotid atherosclerosis.The British journal of radiology · 2015Review
- Prediction of high-risk plaque development and plaque progression with the carotid atherosclerosis score.JACC. Cardiovascular imaging · 2014Article
- Comparison of carotid plaque ulcer detection using contrast-enhanced and time-of-flight MRA techniques.AJNR. American journal of neuroradiology · 2013Article
- Methods for robust in vivo strain estimation in the carotid artery.Physics in medicine and biology · 2012Article
- Assessment of carotid stenosis using three-dimensional T2-weighted dark blood imaging: Initial experience.Journal of magnetic resonance imaging : JMRI · 2012Article
- Review of journal of cardiovascular magnetic resonance 2010.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2011Review
- Review of Journal of Cardiovascular Magnetic Resonance 2009.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2010Review
- MRI of carotid atherosclerosis: clinical implications and future directions.Nature reviews. Cardiology · 2010Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundCarotid atherosclerotic ulceration is a significant source of stroke. This study evaluates the efficacy of adding longitudinal black-blood (BB) cardiovascular magnetic resonance (CMR) angiography to cross-sectional CMR images in the identification of carotid atherosclerotic ulceration.
methodsThirty-two subjects (30 males and two females with ages between 48 and 83 years) scheduled for carotid endarterectomy were imaged on a 1.5T GE Signa scanner using multisequence [3D time-of-flight, T1, proton density, T2, contrast enhanced T1], cross-sectional CMR images and longitudinal BB CMR angiography (0.625 x 0.625 mm/pixel). Two rounds of review (round 1: cross-sectional CMR images alone and round 2: cross-sectional CMR images plus longitudinal BB CMR angiography) were conducted for the presence and volume measurements of ulceration. Ulceration was defined as a distinct depression into the plaque containing blood flow signal on cross-sectional CMR and longitudinal BB CMR angiography.
resultsOf the 32 plaques examined by histology, 17 contained 21 ulcers. Using the longitudinal BB CMR angiography sequence in addition to the cross-sectional CMR images in round 2, the sensitivity improved to 80% for ulcers of at least 6 mm3 in volume by histology and 52.4% for all ulcers, compared to 30% and 23.8% in round 1, respectively. There was a slight decline in specificity from 88.2% to 82.3%, though both the positive and negative predictive values increased modestly from 71.4% to 78.6% and from 48.4% to 58.3%, respectively.
conclusionThe addition of longitudinal BB CMR angiography to multisequence cross-sectional CMR images increases accuracy in the identification of carotid atherosclerotic ulceration.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.