ArticleBMC evolutionary biology2009
Evolutionary dynamics of the LTR retrotransposons roo and rooA inferred from twelve complete Drosophila genomes.
Article in BMC evolutionary biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Pre-Cambrian origin ofeLife · 2026Article
- Nacα protects the larval fat body from cell death by maintaining cellular proteostasis in Drosophila.Nature communications · 2023Article
- Interrogating the 5'UTR tandem repeats of retrotransposon roo of Drosophila about horizontal transfer.Genetica · 2021Article
- Adaptive evolution of an essential telomere protein restricts telomeric retrotransposons.eLife · 2020Article
- Diversification and collapse of a telomere elongation mechanism.Genome research · 2019Article
- Phylogeny of the GenusGenetics · 2018Review
- Article
- Unique transposon landscapes are pervasive across Drosophila melanogaster genomes.Nucleic acids research · 2015Article
- A new genome-wide method to track horizontally transferred sequences: application to Drosophila.Genome biology and evolution · 2014Article
- Article
- Gene duplication in the major insecticide target site, Rdl, in Drosophila melanogaster.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- BEL/Pao retrotransposons in metazoan genomes.BMC evolutionary biology · 2011Article
- Population genomics of transposable elements in Drosophila melanogaster.Molecular biology and evolution · 2011Article
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2 authors.
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Abstract
backgroundRoo is the most abundant retrotransposon in the fruit fly Drosophila melanogaster. Its evolutionary origins and dynamics are thus of special interest for understanding the evolutionary history of Drosophila genome organization. We here study the phylogenetic distribution and evolution of roo, and its highly diverged relative rooA in 12 completely sequenced genomes of the genus Drosophila.
resultsWe identify a total of 164 roo copies, 57 of which were previously unidentified copies that occur in 9 of the 12 genomes. Additionally we find 66 rooA copies in four genomes and remnants of this element in two additional genomes. We further increased the number of elements by searching for individual roo/rooA sequence domains. Most of our roo and rooA elements have been recently inserted. Most elements within a genome are highly similar. A comparison of the phylogenetic tree of our roo and rooA elements shows that the split between roo and rooA took place early in Drosophila evolution. Furthermore there is one incongruency between the species tree and the phylogenetic tree of the roo element. This incongruency regards the placement of elements from D. mojavensis, which are more closely related to D. melanogaster than elements from D. willistoni.
conclusionWithin genomes, the evolutionary dynamics of roo and rooA range from recent transpositional activity to slow decay and extinction. Among genomes, the balance of phylogenetic evidence, sequence divergence distribution, and the occurrence of solo-LTR elements suggests an origin of roo/rooA within the Drosophila clade. We discuss the possibility of a horizontal gene transfer of roo within this clade.
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