ArticleBipolar disorders2009
Can body mass index help predict outcome in patients with bipolar disorder?
Article in Bipolar disorders, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.
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Who cites it
54 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A systematic review and meta-analysis of clinical predictors of lithium response in bipolar disorder.Acta psychiatrica Scandinavica · 2019Pooled it
- The genetic overlap between mood disorders and cardiometabolic diseases: a systematic review of genome wide and candidate gene studies.Translational psychiatry · 2017Pooled it
- Lifestyle interventions targeting dietary habits and exercise in bipolar disorder: A systematic review.Journal of psychiatric research · 2016Pooled it
- Central Obesity-related Brain Alterations Predict Cognitive Impairments in First Episode of Psychosis.Schizophrenia bulletin · 2026Observational
- Demographic and Clinical Correlates of Body Mass Index in Older Age Bipolar Disorder: Results from the GAGE-BD Project.Medicina (Kaunas, Lithuania) · 2026Article
- Insulin Resistance in Bipolar Disorder: A Real-World Cross-Sectional Study.Journal of personalized medicine · 2026Article
- Seasonal metabolic oscillation: adiposity cycling as a candidate amplifier of mood seasonality in seasonal affective and bipolar disorders.Frontiers in psychiatry · 2026Article
- Managing metabolic syndrome in bipolar disorder: multidisciplinary monitoring and treatment strategies.Frontiers in psychiatry · 2026Review
- Article
- Case series: Effects of a ketogenic diet on cardiometabolic health in seven outpatients with bipolar disorder.Frontiers in nutrition · 2025Article
- Effect of prior depression diagnosis on bipolar disorder outcomes: A retrospective cohort study using a medical claims database.Neuropsychopharmacology reports · 2024Article
- Obesity-associated factors in psychiatric outpatients: A multicenter questionnaire survey.Neuropsychopharmacology reports · 2024Article
- Heightened inflammation in bipolar disorder occurs independent of symptom severity and is explained by body mass index.Brain, behavior, & immunity - health · 2023Article
- Assessments of functional outcomes and its determinants among bipolar disorder patients in Northwest Ethiopia comprehensive specialized hospitals: a multicenter hospital-based study.Annals of general psychiatry · 2023Article
- [COVID-19 and Bipolar Affective Disorder: Subjective Changes in Lifestyle Variables During the First Lockdown During the COVID-19 Pandemic in Austria].Fortschritte der Neurologie-Psychiatrie · 2023Article
- Bipolar disorder: an association between body mass index and cingulate gyrus fractional anisotropy not mediated by systemic inflammation.Trends in psychiatry and psychotherapy · 2022Article
- Evaluation of mood disorder questionnaire positivity and associated factors in a population-based screening study.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2022Article
- Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness-ENIGMA study in 2436 individuals.Bipolar disorders · 2022Article
- Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Levels in Adolescent with Bipolar Disorder and Their Relationship with Metabolic Parameters.Journal of molecular neuroscience : MN · 2022Article
- Prevalence and associated factors of obesity and overweight in Chinese patients with bipolar disorder.Frontiers in psychiatry · 2022Article
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8 authors.
Funding
Abstract
objectiveSeveral studies have reported higher prevalence of obesity in patients suffering from bipolar disorder (BD). To study the relation of elevated body mass index (BMI) in patients with BD more closely, we investigated differences in sociodemographic, clinical, and medical characteristics with respect to BMI, with the hypothesis that BMI is related to prognosis and outcome.
methodsWe measured the BMI of 276 subjects of a tertiary care sample from the Maritime Bipolar Registry. Subjects were 16 to 83 years old, with psychiatric diagnoses of bipolar I disorder (n = 186), bipolar II disorder (n = 85), and BD not otherwise specified (n = 5). The registry included basic demographic data and details of the clinical presentation. We first examined the variables showing a significant association with BMI; subsequently, we modeled the relationship between BMI and psychiatric outcome using structural equation analysis.
resultsThe prevalence of obesity in our sample was 39.1%. We found higher BMI in subjects with a chronic course (p < 0.001) and longer duration of illness (p = 0.02), lower scores on the Global Assessment of Functioning Scale (p = 0.02), and on disability (p = 0.002). Overweight patients had more frequent comorbid subthreshold social (p = 0.02) and generalized anxiety disorders (p = 0.05), diabetes mellitus type II (p < 0.001), and hypertension (p = 0.001). Subjects who achieved complete remission of symptoms on lithium showed significantly lower BMI (p = 0.01).
conclusionsOur findings suggest that BMI is associated with the prognosis and outcome of BD. Whether this association is causal remains to be determined.
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