ArticlePloS one2009
A validated genome wide association study to breed cattle adapted to an environment altered by climate change.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of genome-wide association from genomic prediction models.Animal genetics · 2016Pooled it
- Detection of genomic regions affecting thermotolerance traits in growing pigs during acute and chronic heat stress.Genetics, selection, evolution : GSE · 2025Article
- Effect of heat stress on pig production and its mitigation strategies: a review.Tropical animal health and production · 2025Review
- Identification genetic variations in some heat shock protein genes of Tali goat breed and study their structural and functional effects on relevant proteins.Veterinary medicine and science · 2023Article
- Deciphering local adaptation of native Indian cattle (3 Biotech · 2023Article
- Impact of heat stress on dairy cattle and selection strategies for thermotolerance: a review.Frontiers in veterinary science · 2023Review
- Article
- Improving Genomic Selection for Heat Tolerance in Dairy Cattle: Current Opportunities and Future Directions.Frontiers in genetics · 2022Review
- Impact of environmental factors on physiological adaptability, thermo-tolerance indices, and productivity in Jersey crossbred cows.International journal of biometeorology · 2021Article
- The Genetics of Thermoregulation in Pigs: A Review.Frontiers in veterinary science · 2021Review
- Article
- Methylome Patterns of Cattle Adaptation to Heat Stress.Frontiers in genetics · 2021Article
- Spatial modelling improves genetic evaluation in smallholder breeding programs.Genetics, selection, evolution : GSE · 2020Article
- Big dairy data to unravel effects of environmental, physiological and morphological factors on milk production of mountain-pastured Braunvieh cows.Royal Society open science · 2020Article
- RNA-seq profiling of skin in temperate and tropical cattle.Journal of animal science and technology · 2020Article
- Floods, Hurricanes, and Other Catastrophes: A Challenge for the Immune System of Livestock and Other Animals.Frontiers in veterinary science · 2020Review
- Genetic Selection for Thermotolerance in Ruminants.Animals : an open access journal from MDPI · 2019Review
- Genotype by environment interactions for performance and thermoregulation responses in growing pigs1,2.Journal of animal science · 2019Article
- Unraveling genetic sensitivity of beef cattle to environmental variation under tropical conditions.Genetics, selection, evolution : GSE · 2019Article
- Genetic diversity and selection signatures of the beef 'Charolais de Cuba' breed.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Continued production of food in areas predicted to be most affected by climate change, such as dairy farming regions of Australia, will be a major challenge in coming decades. Along with rising temperatures and water shortages, scarcity of inputs such as high energy feeds is predicted. With the motivation of selecting cattle adapted to these changing environments, we conducted a genome wide association study to detect DNA markers (single nucleotide polymorphisms) associated with the sensitivity of milk production to environmental conditions. To do this we combined historical milk production and weather records with dense marker genotypes on dairy sires with many daughters milking across a wide range of production environments in Australia. Markers associated with sensitivity of milk production to feeding level and sensitivity of milk production to temperature humidity index on chromosome nine and twenty nine respectively were validated in two independent populations, one a different breed of cattle. As the extent of linkage disequilibrium across cattle breeds is limited, the underlying causative mutations have been mapped to a small genomic interval containing two promising candidate genes. The validated marker panels we have reported here will aid selection for high milk production under anticipated climate change scenarios, for example selection of sires whose daughters will be most productive at low levels of feeding.
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