ArticleAnnals of the New York Academy of Sciences2009
Neuroregulation of human nasal mucosa.
Article in Annals of the New York Academy of Sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02603588 (Effects of Sphenopalatine Ganglion Acupuncture on Nasal Ventilation and Autonomic Nervous Activity in Healthy Volunteers), which is not on this map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Sphenopalatine Ganglion Acupuncture on Nasal Ventilation and Autonomic Nervous Activity in Healthy Volunteers
Who cites it
16 citing papers in PubMed, 54 citations in OpenAlex.
- Trial
- Inhaled nitrous oxide can reduce the pain perception in post Caldwell-Luc operation patients-a randomised trial.Scientific reports · 2017Trial
- The relationship between allergic rhinitis and sleep disorders and mental health.Frontiers in allergy · 2026Review
- Impact of PMAnnals of medicine · 2025Article
- Assessment of Autonomic Dysfunction in Patients With Empty Nose Syndrome Using the Composite Autonomic Symptom Scale-31.Journal of rhinology : official journal of the Korean Rhinologic Society · 2025Article
- On the nose: nasal neurostimulation as a technology countermeasure for sinonasal congestion in astronauts.Frontiers in physiology · 2025Article
- Sneezing in response to naturalistic bright light exposure.F1000Research · 2025Article
- The role of nociceptive neurons in allergic rhinitis.Frontiers in immunology · 2024Review
- [Advances in etiology and mechanism of structural nasal obstruction].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021Article
- Microbiota Composition and the Integration of Exogenous and Endogenous Signals in Reactive Nasal Inflammation.Journal of immunology research · 2018Review
- Occupational irritant and allergic rhinitis.Current allergy and asthma reports · 2014Review
- Nasal drug delivery in traditional persian medicine.Jundishapur journal of natural pharmaceutical products · 2013Article
- Activation state of the M3 muscarinic acetylcholine receptor modulates mammalian odorant receptor signaling.Science signaling · 2011Article
- Occupational rhinitis and asthma: where do we stand, where do we go?Current allergy and asthma reports · 2010Review
- Physiology and pathophysiology of respiratory mucosa of the nose and the paranasal sinuses.GMS current topics in otorhinolaryngology, head and neck surgery · 2010Article
- Autonomic nervous system dysfunction and sinonasal symptoms.Allergy & rhinology (Providence, R.I.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Multiple subsets of nociceptive, parasympathetic, and sympathetic nerves innervate human nasal mucosa. These play carefully coordinated roles in regulating glandular, vascular, and other processes. These functions are vital for cleaning and humidifying ambient air before it is inhaled into the lungs. The recent identification of distinct classes of nociceptive nerves with unique patterns of transient receptor potential sensory receptor ion channel proteins may account for the polymodal, chemo- and mechanicosensitivity of many trigeminal neurons. Modulation of these families of proteins, excitatory and inhibitory autoreceptors, and combinations of neurotransmitters introduces a new level of complexity and subtlety to nasal innervation. These findings may provide a rational basis for responses to air-temperature changes, culinary and botanical odorants ("aromatherapy"), and inhaled irritants in conditions as diverse as allergic and nonallergic rhinitis, occupational rhinitis, hyposmia, and multiple chemical sensitivity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.