ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2009
Silicone oil induced glaucoma: a review.
Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
97 citing papers in PubMed, 1 synthesis or guideline pooled it, 200 citations in OpenAlex.
- Heavy and standard silicone oil: intraocular inflammation.International ophthalmology · 2018Pooled it
- COHORT SAFETY AND EFFICACY STUDY OF SILURON2000 EMULSIFICATION-RESISTANT SILICONE OIL AND F4H5 IN THE TREATMENT OF FULL-THICKNESS MACULAR HOLE.Retina (Philadelphia, Pa.) · 2015Trial
- Article
- Comparative efficacy of glaucoma drainage device versus ab-interno trabeculotomy in vitrectomized eyes with secondary glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- When Shear and Interfaces Matter: In Vivo Water-in-Silicone Oil Droplet Formation during Long-Term Vitreous Tamponade.ACS omega · 2026Article
- Article
- Complications of silicone oil in vitreoretinal surgery: a narrative review of clinical and experimental evidence.International journal of retina and vitreous · 2026Review
- Risk of Glaucoma after Pars Plana Vitrectomy in a Large Federated Health Record Network.Ophthalmology science · 2026Article
- Article
- F4H5 Alleviates Increased Outflow Resistance Induced by Emulsified Silicone Oil In Vitro.Investigative ophthalmology & visual science · 2025Article
- Silicone Oil Affects Fibrosis of Human Trabecular Meshwork Cells by Upregulating Ferroptosis Through a ROS/NOX4/Smad3 Axis.Investigative ophthalmology & visual science · 2025Article
- Silicon oil glaucoma - surgically escaped by Minimally invasive goniotomy.Eye (London, England) · 2025Article
- Management and toxicological analysis of ocular hypertension after EyeCeeBMC ophthalmology · 2024Article
- The Role of Eye Movements in the Process of Silicone Oil Emulsification After Vitreoretinal Surgery.Bioengineering (Basel, Switzerland) · 2024Article
- Precise prediction of size of a foldable capsular vitreous body via computerized three-dimensional ocular reconstruction in severe retinal detachment.BMC ophthalmology · 2024Article
- Retinal redetachment after silicone oil removal: a risk factor analysis.BMC ophthalmology · 2024Observational
- Challenges of Secondary Glaucoma Management Following Congenital Cataract Surgery, Penetrating Keratoplasty and Vitreoretinal Surgery.Diagnostics (Basel, Switzerland) · 2024Article
- Flow characterization and structural alterations in Ahmed glaucoma FP7 tubes after in-vitro aging in silicone oil.PloS one · 2024Article
- Risk Factors and Management of Intraocular Pressure Elevation After Vitrectomy Combined with Silicone Oil Tamponade.International journal of general medicine · 2024Review
- Combining Perfluorobutylpentane (FTurkish journal of ophthalmology · 2023Article
37 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSilicone oil has been an important adjunct for internal tamponade in the treatment of complicated retinal detachment for the past 4 decades. A known complication of its use has been the development of secondary glaucoma.
methodsThis article reviews the current body of literature documenting the different pathogeneses, predisposing factors and management of silicone oil induced pressure elevation and optic neuropathy. Categorization is clarified for the different types of secondary glaucomas due to silicone oil.
resultsFour different mechanisms have been proposed for the pathogenesis of glaucoma that require different therapeutic strategies: (1) overfill with total anterior chamber fill leads to an open-angle glaucoma due to mechanical obstruction of outflow, (2) pupillary block with silicone oil incites angle closure glaucoma, (3) denaturation of silicone oil into microdroplets may sweep into the trabecular meshwork with the development of secondary open angle glaucoma, or (4) finally, inflammation or exacerbation of pre-existing glaucoma.
conclusionUnderstanding the risk factors and the pathogenesis of secondary glaucoma when using silicone oil helps guide the timely and appropriate course of treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.