Evidence map›Paper›PMID 19684877›Full record

ArticleProceedings of the IEEE. Institute of Electrical and Electronics Engineers2004

Dielectrophoresis-Based Sample Handling in General-Purpose Programmable Diagnostic Instruments.

Peter R C Gascoyne, Jody V Vykoukal

Abstract read
In one paragraph

Article in Proceedings of the IEEE. Institute of Electrical and Electronics Engineers, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Tutorial on Lateral Dielectrophoretic Manipulations in Microfluidic Systems.IEEE transactions on biomedical circuits and systems · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Hardware Design and Fault-Tolerant Synthesis for Digital Acoustofluidic Biochips.IEEE transactions on biomedical circuits and systems · 2020
    Article
  14. Highly Localized Enrichment ofMicromachines · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter R C GascoyneDepartment of Molecular Pathology, M.D., Anderson Cancer Center, University of Texas, Houston, TX 77030 USA.
Jody V Vykoukal

Funding

INTEGRATED ISOLATION &MOLECULAR ANALYSIS OF TUMOR CELLSR33CA088364 · NCI · UNIVERSITY OF TEXAS MD ANDERSON CAN CTR · PI GASCOYNE, PETER RUSSELL CHARLES · 2001 to 2003
$1.6M
NCI NIH HHS R33 CA088364
6 · The paper itself

Abstract

As the molecular origins of disease are better understood, the need for affordable, rapid, and automated technologies that enable microscale molecular diagnostics has become apparent. Widespread use of microsystems that perform sample preparation and molecular analysis could ensure that the benefits of new biomedical discoveries are realized by a maximum number of people, even those in environments lacking any infrastructure. While progress has been made in developing miniaturized diagnostic systems, samples are generally processed off-device using labor-intensive and time-consuming traditional sample preparation methods. We present the concept of an integrated programmable general-purpose sample analysis processor (GSAP) architecture where raw samples are routed to separation and analysis functional blocks contained within a single device. Several dielectrophoresis-based methods that could serve as the foundation for building GSAP functional blocks are reviewed including methods for cell and particle sorting, cell focusing, cell ac impedance analysis, cell lysis, and the manipulation of molecules and reagent droplets.

Identifiers

PMID19684877
PMCPMC2726756

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.