ArticleNature methods2009
Isolation of deletion alleles by G4 DNA-induced mutagenesis.
Article in Nature methods, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- CNBP Binds and Unfolds In Vitro G-Quadruplexes Formed in the SARS-CoV-2 Positive and Negative Genome Strands.International journal of molecular sciences · 2021Article
- Guanine Quadruplex DNA Regulates Gamma Radiation Response of Genome Functions in the Radioresistant BacteriumJournal of bacteriology · 2019Article
- Mechanical insights into ribosomal progression overcoming RNA G-quadruplex from periodical translation suppression in cells.Scientific reports · 2016Article
- Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers.Nature communications · 2015Article
- Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation.BMC genomics · 2015Article
- Forward and reverse mutagenesis in C. elegans.WormBook : the online review of C. elegans biology · 2014Review
- A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro.Nucleic acids research · 2012Article
- What does physics have to do with cancer?Nature reviews. Cancer · 2011Review
- DNA secondary structures and epigenetic determinants of cancer genome evolution.Nature structural & molecular biology · 2011Article
- How long is too long? Effects of loop size on G-quadruplex stability.Nucleic acids research · 2010Article
- Targeted gene deletions in C. elegans using transposon excision.Nature methods · 2010Article
- From genes to function: the C. elegans genetic toolbox.Wiley interdisciplinary reviews. Developmental biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metazoan genomes contain thousands of sequence tracts that match the guanine-quadruplex (G4) DNA signature G(3)N(x)G(3)N(x)G(3)N(x)G(3), a motif that is intrinsically mutagenic, probably because it can form secondary structures during DNA replication. Here we show how and to what extent this feature can be used to generate deletion alleles of many Caenorhabditis elegans genes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.