Evidence map›Paper›PMID 19680766›Full record

ArticleFish physiology and biochemistry2010

Epigallocatechin-3-gallate (EGCG) affects the antioxidant and immune defense of the rainbow trout, Oncorhynchus mykiss.

J Thawonsuwan, V Kiron, S Satoh, A Panigrahi, V Verlhac

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Fish physiology and biochemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 96 citations in OpenAlex.

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  14. Skin Protective Effect of Epigallocatechin Gallate.International journal of molecular sciences · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

J ThawonsuwanCoastal Aquatic Animal Health Research Institute, Pawong, Muang, Songkla, 90100, Thailand.
V KironFaculty of Biosciences and Aquaculture, Bodø University College, Bodø, 8049, Norway. kiron.viswanath@hibo.no.
S SatohDepartment of Marine Biosciences, Tokyo University of Marine Science and Technology, Minato, Tokyo, 108-8477, Japan.
A PanigrahiCentral Institute of Brackishwater Aquaculture, KRC, Kakdwip, West Bengal, 743347, India.
V VerlhacAquaculture Research Group, DSM Nutritional Products, CRNA-BP170, 68305, St. Louis cedex, France.
Central Institute of Brackishwater Aquaculture · INTokyo University of Marine Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigallocatechin-3-gallate (EGCG), a very potent antioxidant derived from green tea, was compared with vitamin E in terms of its effects on antioxidant defense and immune response of rainbow trout, by means of a feeding trial of eight weeks. Two of the experimental diets were supplemented with EGCG at either 20 or 100 mg kg(-1) diet (which contained only 30% of the intended levels) and the third was provided with 100 mg kg(-1) vitamin E but not EGCG. The control diet was not supplemented with the test components. Observation of tissue levels indicated that the high amount of EGCG helped to increase the availability of the lipid-soluble antioxidant vitamin E. The lower levels of lipid hydroperoxide in the liver of fish fed the higher amount of EGCG suggested that it was an effective antioxidant. Considering the immune indices, EGCG and vitamin E at 100 mg (actual amounts 31.9 and 94.1 mg kg(-1) diet, respectively) had identical capabilities in improving phagocytic activity and controlling hydrogen peroxide production by leucocytes. However, EGCG could possibly be more effective at enhancing serum lysozyme activity and the alternative complement activity. This work revealed the potential of EGCG as an antioxidant and an immunostimulant for rainbow trout, at least at the inclusion level of 32 mg kg(-1) diet.

Indexed as

Analysis of VarianceAnimalsAntioxidantsCatechinComplement Pathway, AlternativeDietary SupplementsFlow CytometryLipid PeroxidesLiverMuramidaseOncorhynchus mykissReactive Oxygen SpeciesSuperoxide DismutaseVitamin EAntioxidantsCatechinepigallocatechin gallateLipid PeroxidesMuramidaseReactive Oxygen SpeciesSuperoxide DismutaseVitamin E

Identifiers

PMID19680766
OpenAlexW1999375522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.