Evidence map›Paper›PMID 19680249›Full record

ReviewNature reviews. Microbiology2009

The type III secretion system of Pseudomonas aeruginosa: infection by injection.

Alan R Hauser

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 554 papers.

0numbers the graph read from it
0cells of the map it votes in
554citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

554 citing papers in PubMed.

  1. Article
  2. Review
  3. Temperature-dependent reprogramming of virulence traits duringbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Applicability of Nanopore-only whole-genome sequencing forJournal of clinical microbiology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

494 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Alan R HauserDepartments of MicrobiologyImmunology and Medicine, Northwestern University, Chicago, Illinois 60611, USA. ahauser@northwestern.edu

Funding

Mechanistic Studies of Patatin-like ToxinsR01AI053674 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAUSER, ALAN R · 2003 to 2017
$4.3M
Pseudomonas aeruginosa Genomic Islands and VirulenceR01AI075191 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAUSER, ALAN R · 2009 to 2013
$1.7M
Novel Pathogenicity islands of Pseudomonas aeruginosaK02AI065615 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAUSER, ALAN R · 2005 to 2009
$496k
NIAID NIH HHS K02 AI065615NIAID NIH HHS R01 AI053674NIAID NIH HHS R01 AI075191
6 · The paper itself

Abstract

The Gram-negative bacterium Pseudomonas aeruginosa uses a complex type III secretion apparatus to inject effector proteins into host cells. The configuration of this secretion machinery, the activities of the proteins that are injected by it and the consequences of this process for infection are now being elucidated. This Review summarizes our current knowledge of P. aeruginosa type III secretion, including the secretion and translocation machinery, the regulation of this machinery, and the associated chaperones and effector proteins. The features of this interesting secretion system have important implications for the pathogenesis of P. aeruginosa infections and for other type III secretion systems.

Indexed as

Bacterial ProteinsGenes, BacterialHumansMembrane Transport ProteinsModels, BiologicalMultigene FamilyProtein TransportPseudomonas aeruginosaPseudomonas InfectionsVirulence FactorsBacterial ProteinsMembrane Transport ProteinsVirulence Factors

Identifiers

PMID19680249
PMCPMC2766515

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.