Evidence map›Paper›PMID 19679518›Full record

ReviewAutonomic neuroscience : basic & clinical2010

Visceral organ cross-sensitization - an integrated perspective.

P R Brumovsky, G F Gebhart

Abstract readReview
In one paragraph

Review in Autonomic neuroscience : basic & clinical, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. A multidimensional appraisal of early menstrual pain experience.American journal of obstetrics and gynecology · 2024
    Article
  8. Article
  9. Intestinal neuropod cell GUCY2C regulates visceral pain.The Journal of clinical investigation · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Spinal neuron-glia-immune interaction in cross-organ sensitization.American journal of physiology. Gastrointestinal and liver physiology · 2020
    Review
  16. Article
  17. Co-occurrence of pain syndromes.Journal of neural transmission (Vienna, Austria : 1996) · 2020
    Review
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P R BrumovskyPittsburgh Center for Pain Research, Department of Anesthesiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. Pablo_Brumovsky@yahoo.com
G F Gebhart

Funding

PRIMARY VISCERAL AFFERENTS IN PAINR01NS035790 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAVIS, BRIAN M · 1997 to 2014
$5.1M
MECHANISMS AND MODULATION OF VISCERAL PAINR01NS019912 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GEBHART, GERALD F · 1985 to 2009
$3.7M
NINDS NIH HHS NS 19912NINDS NIH HHS NS 35790NINDS NIH HHS R01 NS019912NINDS NIH HHS R01 NS035790
6 · The paper itself

Abstract

Viscero-somatic referral and sensitization has been well documented clinically and widely investigated, whereas viscero-visceral referral and sensitization (termed cross-organ sensitization) has only recently received attention as important to visceral disease states. Because second order neurons in the CNS have been extensively shown to receive convergent input from different visceral organs, it has been assumed that cross-organ sensitization arises by the same convergence-projection mechanism as advanced for viscero-somatic referral and sensitization. However, increasing evidence also suggests participation of peripheral mechanisms to explain referral and sensitization. We briefly summarize behavioral, morphological and physiological support of and focus on potential mechanisms underlying cross-organ sensitization.

Indexed as

AnimalsAutonomic Nervous SystemCentral Nervous SystemGastrointestinal TractHumansMechanotransduction, CellularSense OrgansSkinUrinary BladderVisceral Afferents

Identifiers

PMID19679518
PMCPMC2818077

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.