ReviewNature2009
Structure-function relationships of anaerobic gas-processing metalloenzymes.
Review in Nature, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed.
- Integrated chaperone engineering and process optimization enable enhanced production of ChCODH-II A559W in Escherichia coli.World journal of microbiology & biotechnology · 2026Article
- Access to Heterobimetallic MInorganic chemistry · 2025Article
- Electrocatalytic COChemical science · 2024Article
- Implementation of a high cell density fed-batch for heterologous production of active [NiFe]-hydrogenase in Escherichia coli bioreactor cultivations.Microbial cell factories · 2022Article
- Second and Outer Coordination Sphere Effects in Nitrogenase, Hydrogenase, Formate Dehydrogenase, and CO Dehydrogenase.Chemical reviews · 2022Review
- Time-Resolved Infrared Spectroscopy Reveals the pH-Independence of the First Electron Transfer Step in the [FeFe] Hydrogenase Catalytic Cycle.The journal of physical chemistry letters · 2022Article
- Oxygen-Sensitive Metalloprotein Structure Determination by Cryo-Electron Microscopy.Biomolecules · 2022Article
- Functional Conversion of Acetyl-Coenzyme a Synthase to a Nickel Superoxide Dismutase via Rational Design of Coordination Microenvironment for the NiInternational journal of molecular sciences · 2022Article
- Applications of Carbon Dots for the Photocatalytic and Electrocatalytic Reduction of COMolecules (Basel, Switzerland) · 2022Review
- Heterologous Hydrogenase Overproduction Systems for Biotechnology-An Overview.International journal of molecular sciences · 2020Review
- Structure, function, and biosynthesis of nickel-dependent enzymes.Protein science : a publication of the Protein Society · 2020Review
- Tuning Catalytic Bias of Hydrogen Gas Producing Hydrogenases.Journal of the American Chemical Society · 2020Article
- Combination of Trace Metal to Improve Solventogenesis ofFrontiers in microbiology · 2020Article
- Nickel Metalloregulators and Chaperones.Inorganics · 2019Article
- Iron Carbide-Sulfide Carbonyl Clusters.Inorganic chemistry · 2019Article
- Computational Approach to Molecular Catalysis by 3d Transition Metals: Challenges and Opportunities.Chemical reviews · 2019Article
- The Birthplace of Proto-Life: Role of Secondary Minerals in Forming Metallo-Proteins through Water-Rock Interaction of Hadean Rocks.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2018Article
- Spectroscopical Investigations on the Redox Chemistry of [FeFe]-Hydrogenases in the Presence of Carbon Monoxide.Molecules (Basel, Switzerland) · 2018Article
- Biophysical and structural characterization of the putative nickel chaperone CooT from Carboxydothermus hydrogenoformans.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2018Article
- From protein engineering to artificial enzymes - biological and biomimetic approaches towards sustainable hydrogen production.Sustainable energy & fuels · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reactions involving H(2), N(2), CO, CO(2) and CH(4) are likely to have been central to the origin of life. This is indicated by the active-site structures of the enzymes involved, which are often reminiscent of minerals. Through the combined efforts of protein crystallography, various types of spectroscopy, theoretical calculations and model chemistry, it has been possible to put forward plausible mechanisms for gas-based metabolism by extant microorganisms. Although the reactions are based on metal centres, the protein matrix regulates reactivity and substrate and product trafficking through internal pathways, specific ligation and dielectricity.
Indexed as
Identifiers
19675641What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.