Evidence map›Paper›PMID 19675355›Full record

ReviewPhysiology (Bethesda, Md.)2009

What's new about osmotic regulation of glycerophosphocholine.

Morgan Gallazzini, Maurice B Burg

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Morgan GallazziniDepartment of Health and Human Services, Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Maurice B Burg

Funding

ROLE OF ORGANIC OSMOLYTES IN RENAL CELLSZ01HL001283 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI BURG, MAURICE BENJAM · 1988 to 2008
$3.8M
Response Of Renal Cells To Osmotic StressZIAHL001283 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI BURG, MAURICE BENJAM · 2009 to 2010
$3.5M
Intramural NIH HHS ZIA HL001283
6 · The paper itself

Abstract

Glycerophosphocholine is an abundant renal medullary organic osmolyte that protects renal medullary cells from the high interstitial concentrations of NaCl and urea to which they are normally exposed. We consider the metabolism of glycerophosphocholine, its osmotic regulation, and the recently discovered molecular identity of the enzymes that osmoregulate its abundance.

Indexed as

AnimalsGlycerylphosphorylcholineHumansKidney MedullaSodium ChlorideUreaWater-Electrolyte BalanceGlycerylphosphorylcholineSodium ChlorideUrea

Identifiers

PMID19675355
PMCPMC2943332

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.