ArticleDiabetes care2009
Vitamin D levels in subjects with and without type 1 diabetes residing in a solar rich environment.
Article in Diabetes care, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Does vitamin D affect risk of developing autoimmune disease?: a systematic review.Seminars in arthritis and rheumatism · 2011Pooled it
- Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study.PLoS medicine · 2021Trial
- No effect of the 1alpha,25-dihydroxyvitamin D3 on beta-cell residual function and insulin requirement in adults with new-onset type 1 diabetes.Diabetes care · 2010Trial
- The vitamin D receptor TaqI TT genotype is associated with type 1 diabetes in the Black South African population.Journal of nutritional science · 2024Observational
- 25OHVitamin D Levels in a Canarian Pediatric Population with and without Type 1 Diabetes: The Role of Acidosis.Nutrients · 2023Article
- Vitamin D Status in Diabetic Moroccan Children And Adolescents: a Case-control Study.The review of diabetic studies : RDS · 2023Article
- Vitamin D status in longstanding type 1 diabetes and controls. Association with upper extremity impairments.Upsala journal of medical sciences · 2023Article
- Vitamin D as a Nutri-Epigenetic Factor in Autoimmunity-A Review of Current Research and Reports on Vitamin D Deficiency in Autoimmune Diseases.Nutrients · 2022Review
- Stress Hyperglycemia in Children and Adolescents as a Prognostic Indicator for the Development of Type 1 Diabetes Mellitus.Frontiers in pediatrics · 2021Review
- Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci.American journal of human genetics · 2020Article
- The Challenges of Identifying Environmental Determinants of Type 1 Diabetes: In Search of the Holy Grail.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Review
- Confirmation and Identification of Biomarkers Implicating Environmental Triggers in the Pathogenesis of Type 1 Diabetes.Frontiers in immunology · 2020Article
- Quantitation of serum 25(OH)D2 and 25(OH)D3 concentrations by liquid chromatography tandem mass spectrometry in patients with diabetes mellitus.Journal of food and drug analysis · 2019Article
- Low levels of 25-hydroxyvitamin D in children and adolescents with type 1 diabetes mellitus: a single center experience.Annals of pediatric endocrinology & metabolism · 2018Article
- Serum adipokines and vitamin D levels in patients with type 1 diabetes mellitus.Archives of medical science : AMS · 2017Article
- New light on an old vitamin: The role of the sunshine vitamin D in chronic disease.Reviews in endocrine & metabolic disorders · 2017Article
- Vitamin D status in youth with type 1 and type 2 diabetes enrolled in the Pediatric Diabetes Consortium (PDC) is not worse than in youth without diabetes.Pediatric diabetes · 2016Article
- Low serum vitamin-D status is associated with high prevalence and early onset of type-1 diabetes mellitus in Kuwaiti children.BMC pediatrics · 2016Article
- FGF-23/Vitamin D Axis in Type 1 Diabetes: The Potential Role of Mineral Metabolism in Arterial Stiffness.PloS one · 2015Article
- Prevalence of vitamin D deficiency in pre-type 1 diabetes and its association with disease progression.Diabetologia · 2014Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePrevious studies, largely in northern Europe, have suggested an association between type 1 diabetes and reduced serum 25-hydroxy(OH) vitamin D levels, a concept we tested in individuals residing in a solar-rich region (Florida). RESEARCH DESIGN AND
methodsSerum samples from 415 individuals residing in Florida were cross-sectionally analyzed: 153 control subjects, 46 new-onset type 1 diabetic patients, 110 established type 1 diabetic patients (samples >or=5 months from diagnosis), and 106 first-degree relatives of the diabetic patients.
resultsIn this study, 25-OH vitamin D levels (median, range, interquartile range [IQR]) were similar among control subjects (20.1, below detection [bd]-163.5, 13.0-37.4 ng/ml), new-onset type 1 diabetic patients (21.2, bd-48.6, 12.2-30.2 ng/ml), established type 1 diabetic patients (23.2, bd-263.8, 13.8-33.9 ng/ml), and first-degree relatives (22.2, bd-59.9, 12.7-33.1 ng/ml) (P = 0.87). Mean 25-OH vitamin D levels were less than the optimal World Health Organization level of 30 ng/ml in all study groups.
conclusionsReduced serum 25-OH vitamin D levels were not specifically associated with type 1 diabetes. The uniform suboptimal 225-OH vitamin D levels, despite residence in a zone with abundant sunshine, support additional dietary vitamin D fortification practices.
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