ArticleBMC pediatrics2009
Prioritising neonatal medicines research: UK Medicines for Children Research Network scoping survey.
Article in BMC pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Development and Evaluation of a Gentamicin Pharmacokinetic Model That Facilitates Opportunistic Gentamicin Therapeutic Drug Monitoring in Neonates and Infants.Antimicrobial agents and chemotherapy · 2016Pooled it
- Drug utilisation in neonatal units in England and Wales: a national cohort study.European journal of clinical pharmacology · 2022Observational
- Protocol: Pentoxifylline optimal dose finding trial in preterm neonates with suspected late onset sepsis (PTX-trial).BMC pediatrics · 2021Article
- Review of Drug Utilization Studies in Neonatal Units: A Global Perspective.International journal of environmental research and public health · 2020Review
- "How can a drug to treat claudication in adults save preterm newborns?"European journal of pediatrics · 2020Article
- Cross-sectional study of drug utilisation in a Chinese neonatal unit.The Journal of international medical research · 2020Article
- Top research priorities for preterm birth: results of a prioritisation partnership between people affected by preterm birth and healthcare professionals.BMC pregnancy and childbirth · 2019Article
- Aminoglycoside-induced nephrotoxicity in children.Pediatric nephrology (Berlin, Germany) · 2017Review
- Drug utilisation profile in the neonatal unit of a university hospital: a prospective observational study in Brazil.International journal of clinical pharmacy · 2015Observational
- Clinical trials of medicines in neonates: the influence of ethical and practical issues on design and conduct.British journal of clinical pharmacology · 2015Review
- Educational paper: do we need neonatal clinical pharmacologists?European journal of pediatrics · 2013Review
- Adverse Drug Reactions in Children: Pediatric Pharmacy and Drug Safety.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAGArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe dosing regimen and indications for many medicines in current use in neonatology are not well defined. There is a need to prioritise research in this area, but currently there is little information about which drugs are used in UK neonatal units and the research needs in this area as perceived by UK neonatologists.
methodsThe Neonatal Clinical Studies Group (CSG) of the Medicines for Children Research Network (MCRN) undertook a 2 week prospective scoping survey study to establish which medicines are used in UK neonatal units; how many babies are receiving them; and what clinicians (and other health professionals) believe are important issues for future research.
results49 out of 116 units responded to at least one element of the survey (42%). 37 units reported the number of neonates who received medicines over a 2 week period. A total of 3924 medicine-patient pairs were reported with 119 different medicines. 70% of medicine-patient pairs involved medicines that were missing either a license or dose for either term or preterm neonates. 4.3% of medicine-patient pairs involved medicines that were missing both license and dose for any neonate. The most common therapeutic gap in need of additional research identified by UK neonatologists was chronic lung disease (21 responding units), followed by patent ductus arteriosus and vitamin supplements (11 responding units for both)
conclusionThe research agenda for neonatal medicines can be informed by knowledge of current medicine use and the collective views of the neonatal community.
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