ArticleCephalalgia : an international journal of headache2010
MTHFR 677C->T and ACE D/I polymorphisms and migraine attack frequency in women.
Article in Cephalalgia : an international journal of headache, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of genome-wide association for migraine in six population-based European cohorts.European journal of human genetics : EJHG · 2011Pooled it
- Article
- Single Nucleotide Variants (SNVs) of Angiotensin-Converting Enzymes (ACE1 and ACE2): A Plausible Explanation for the Global Variation in COVID-19 Prevalence.Journal of the renin-angiotensin-aldosterone system : JRAAS · 2023Review
- Glucose-Related Traits and Risk of Migraine-A Potential Mechanism and Treatment Consideration.Genes · 2022Review
- Association of endothelial nitric oxide synthase gene polymorphisms (894G/T, -786T/C, G10T) and clinical findings in patients with migraine.Neuromolecular medicine · 2014Article
- Investigation of MTHFR C677T gene polymorphism, biochemical and clinical parameters in Turkish migraine patients: association with allodynia and fatigue.Cellular and molecular neurobiology · 2013Article
- Effects of MTHFR gene polymorphism on the clinical and electrophysiological characteristics of migraine.BMC neurology · 2013Article
- Lack of association between the MTHFR C677T variant and migraine with aura in an older population: could selective survival play a role?Cephalalgia : an international journal of headache · 2013Article
- MAOA, MTHFR, and TNF-β genes polymorphisms and personality traits in the pathogenesis of migraine.Molecular and cellular biochemistry · 2012Article
- Methylenetetrahydrofolate reductase gene variant (MTHFR C677T) and migraine: a case control study and meta-analysis.BMC neurology · 2011Article
- Identification of molecular genetic factors that influence migraine.Molecular genetics and genomics : MGG · 2011Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Data on the association of the MTHFR 677C→T and ACE D/I polymorphisms with migraine severity, measured by attack frequency, are scarce. We performed an association study among 24 961 women participating in the Women's Health Study. Migraine, aura status and attack frequency were self-reported. Multinomial logistic regression was used to investigate the genotype-migraine association. Among the 3186 migraineurs with complete genotype and attack frequency data, 1270 reported migraine with aura (MA) (attack frequency 76 ≥ weekly; 219 monthly; 123 every other month; 852 fewer than six times/year) and 1916 migraine without aura (MoA) (attack frequency: 85 ≥ weekly; 414 monthly; 208 every other month; 1209 fewer than six times/year). The MTHFR 677TT genotype was associated with a reduced risk for MA, which only appeared for attacks fewer than six times/year (age-adjusted odds ratio 0.78; 95% confidence interval 0.61, 0.99). We did not find a specific pattern of association of the ACE D/I polymorphism with attack frequency for MA or MoA.
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