ArticleJournal of the American Chemical Society2009
Fluorinated lipid constructs permit facile passage of molecular cargo into living cells.
Article in Journal of the American Chemical Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 29 citations in OpenAlex.
- Counterion Exchange Enhances the Brightness and Photostability of a Fluorous Cyanine Dye.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024Article
- Optimized biomimetic minerals maintain activity of mRNA complexes after long term storage.Acta biomaterialia · 2024Article
- Deciphering the Mechanistic Basis for Perfluoroalkyl-Protein Interactions.Chembiochem : a European journal of chemical biology · 2023Article
- Perfluorocarbons in Chemical Biology.Chembiochem : a European journal of chemical biology · 2020Review
- A General Approach to Biocompatible Branched Fluorous Tags for Increased Solubility in Perfluorocarbon Solvents.Organic letters · 2018Article
- The fluorination effect of fluoroamphiphiles in cytosolic protein delivery.Nature communications · 2018Article
- Structure-Based Design of Dendritic Peptide Bolaamphiphiles for siRNA Delivery.ACS central science · 2015Article
- Synthetic cell surface receptors for delivery of therapeutics and probes.Advanced drug delivery reviews · 2012Review
- Toward a general approach for RNA-templated hierarchical assembly of split-proteins.Journal of the American Chemical Society · 2010Article
- A New Paradigm for Protein Design and Biological Self-Assembly.Journal of fluorine chemistry · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Fluorinated lipids get rapidly internalized into living cells and are also displayed on the cell surface. The uptake of lipids is energy dependent and is likely via the clathrin-mediated endocytic pathway. Fluorinated lipids are 3-5-fold more efficient in acting as molecular transporters of noncovalently bound proteins than their hydrocarbon counterparts. These materials could serve as efficient molecular transporters for molecules that function in the cytoplasm such as short interfering RNAs (siRNAs).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.