Evidence map›Paper›PMID 19672890›Full record

ArticleEuropean journal of immunology2009

Update on animal models for HIV research.

Nancy L Haigwood

Abstract read
In one paragraph

Article in European journal of immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Nonpathogenic simian immunodeficiency virus infections.Cold Spring Harbor perspectives in medicine · 2012
    Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Nancy L HaigwoodOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. haigwoon@ohsu.edu

Funding

YR 50 PROJ- ROBERTS PRIMATE ISLETP51RR000163 · NCRR · OREGON REGIONAL PRIMATE RESEARCH CENTER · PI FRUH, KLAUS J · 1985 to 2011
$140.8M
Vaccination design based on natural env genes to elicit broad neutralizing AbsP01AI078064 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI HAIGWOOD, NANCY L · 2009 to 2014
$12.1M
Role of Neutralizing Antibodies in Transmission of SHIVR01HD038653 · NICHD · SEATTLE BIOMEDICAL RESEARCH INSTITUTE · PI HAIGWOOD, NANCY L · 2000 to 2010
$3.8M
Novel antigen display system to present multiple antigens HIV vaccinesR01AI074379 · NIAID · SEATTLE BIOMEDICAL RESEARCH INSTITUTE · PI HAIGWOOD, NANCY L · 2007 to 2011
$1.9M
REPRODUCTIVE STEROIDS AND EXPERIMENTAL STROKEK01RR000163 · NCRR · OREGON HEALTH AND SCIENCE UNIVERSITY · PI MURPHY, STEPHANIE J · 2000 to 2004
$479k
NCRR NIH HHS K01 RR000163NCRR NIH HHS P51 RR000163NCRR NIH HHS RR00163NIAID NIH HHS AI074379NIAID NIH HHS AI078064NIAID NIH HHS P01 AI078064NIAID NIH HHS R01 AI074379NICHD NIH HHS HD38653NICHD NIH HHS R01 HD038653
6 · The paper itself

Abstract

Animal models for HIV research have been indispensible in fulfilling Koch's postulate and in exploring issues of viral infectivity and pathogenesis, sequence divergence, route(s) of acquisition, tissue distribution and tropism, immunogenicity and protection capacity of vaccine candidates, escape from adaptive immunity, and more. Did they fail to predict the efficacy of T-cell vaccines in humans? This article summarizes progress and status of models to inform and complement clinical work.

Indexed as

Disease Models, AnimalAcquired Immunodeficiency SyndromeAIDS VaccinesAnimalsAntiretroviral Therapy, Highly ActiveAntiviral AgentsBiomedical ResearchHIV-1HumansMacacaSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAIDS VaccinesAntiviral Agents

Identifiers

PMID19672890
PMCPMC2866064

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.