Evidence map›Paper›PMID 19672455›Full record

ReviewJournal of biomedicine & biotechnology2009

TIS11 family proteins and their roles in posttranscriptional gene regulation.

Maria Baou, Andrew Jewell, John J Murphy

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of biomedicine & biotechnology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
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  8. RNA-Binding Proteins in Acute Leukemias.International journal of molecular sciences · 2020
    Review
  9. Review
  10. Article
  11. Closed-loop cycles of experiment design, execution, and learning accelerate systems biology model development in yeast.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Review
  12. Article
  13. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Maria BaouDivision of Immunology Infection and Inflammatory Disease, King's College London, and St George's Hospital, London WC2R 2LS, UK.
Andrew Jewell
John J Murphy
King's College London · GBKingston University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posttranscriptional regulation of gene expression of mRNAs containing adenine-uridine rich elements (AREs) in their 3' untranslated regions is mediated by a number of different proteins that interact with these elements to either stabilise or destabilise them. The present review concerns the TPA-inducible sequence 11 (TIS11) protein family, a small family of proteins, that appears to interact with ARE-containing mRNAs and promote their degradation. This family of proteins has been extensively studied in the past decade. Studies have focussed on determining their biochemical functions, identifying their target mRNAs, and determining their roles in cell functions and diseases.

Indexed as

Gene Expression RegulationRNA Processing, Post-TranscriptionalAnimalsHumansTristetraprolinTristetraprolin

Identifiers

PMID19672455
PMCPMC2722025
OpenAlexW2031032967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.