Evidence map›Paper›PMID 19671378›Full record

ReviewCurrent allergy and asthma reports2009

Mast cell modulation of the immune response.

John J Ryan, Josephine F Fernando

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis.Journal of immunology (Baltimore, Md. : 1950) · 2012
    Article
  3. Article
  4. Mast cell function and death in Trypanosoma cruzi infection.The American journal of pathology · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John J RyanDepartment of Biology, Virginia Commonwealth University, Richmond, VA 23284-2012, USA. jjryan@vcu.edu
Josephine F Fernando

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mast cells are present in nearly all vascularized tissues, but not the blood. They are best known for the prominent role they play in atopic disease. However, our current understanding of their direct and indirect roles in the immune response offers a more nuanced picture of both villain and hero. Although they are implicated in many inflammatory disorders, they also defend us from bacterial pathogens, prevent dangerous overreactions by the immune system, and even protect us from snake venom. Perhaps there is more to these maligned cells than we thought.

Indexed as

AnimalsCell CommunicationCytokinesHumansImmune ToleranceImmunity, ActiveImmunoglobulin EImmunologic FactorsInflammationMast CellsProtein KinasesReceptors, IgESignal TransductionT-Lymphocyte SubsetsCytokinesImmunoglobulin EImmunologic FactorsProtein KinasesReceptors, IgE

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.