ArticleCritical care (London, England)2009
Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients: an observational study.
Article in Critical care (London, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Reproducibility of transpulmonary thermodilution cardiac output measurements in clinical practice: a systematic review.Journal of clinical monitoring and computing · 2017Pooled it
- Similar hemodynamic decongestion with vasodilators and inotropes: systematic review, meta-analysis, and meta-regression of 35 studies on acute heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Pooled it
- Association Between Myocardial Dysfunction and Septic Shock.International journal of molecular sciences · 2026Review
- The Role of Pyroptosis in Exacerbating Sepsis-Induced Myocardial Injury: Mechanisms and Implications.Journal of inflammation research · 2026Review
- Subclinical cardiac dysfunction may impact on fluid and vasopressor administration during early resuscitation of septic shock.Journal of anesthesia, analgesia and critical care · 2023Article
- Research Progress on the Mechanism and Management of Septic Cardiomyopathy: A Comprehensive Review.Emergency medicine international · 2023Review
- Volumetric Monitoring and Extravascular Lung Water in Perioperative Setting and Critically Ill.Turkish journal of anaesthesiology and reanimation · 2021Article
- Real-world extravascular lung water index measurements in critically ill patients : Pulse index continuous cardiac output measurements: time course analysis and association with clinical characteristics.Wiener klinische Wochenschrift · 2019Article
- Extravascular lung water index and Halperin score to predict outcome in critically ill patients.Wiener klinische Wochenschrift · 2018Article
- Alternatives to the Swan-Ganz catheter.Intensive care medicine · 2018Review
- Midazolam increases preload dependency during endotoxic shock in rabbits by affecting venous vascular tone.Annals of intensive care · 2018Article
- Effect of Systolic Cardiac Function on Passive Leg Raising for Predicting Fluid Responsiveness: A Prospective Observational Study.Chinese medical journal · 2018Observational
- Observational
- Validation of transpulmonary thermodilution variables in hemodynamically stable patients with heart diseases.Annals of intensive care · 2017Article
- Organ dysfunction, injury and failure in acute heart failure: from pathophysiology to diagnosis and management. A review on behalf of the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).European journal of heart failure · 2017Review
- Consistency of cardiac function index and global ejection fraction with global end-diastolic volume in patients with femoral central venous access for transpulmonary thermodilution: a prospective observational study.Journal of clinical monitoring and computing · 2017Observational
- Pulse contour cardiac output monitoring in acute heart failure patients : Assessment of hemodynamic measurements.Wiener klinische Wochenschrift · 2016Article
- Accuracy of an autocalibrated pulse contour analysis in cardiac surgery patients: a bi-center clinical trial.BMC anesthesiology · 2015Article
- Is there a role for invasive hemodynamic monitoring in acute heart failure management?Current heart failure reports · 2015Review
- Dynamic arterial elastance predicts mean arterial pressure decrease associated with decreasing norepinephrine dosage in septic shock.Critical care (London, England) · 2015Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThere is limited clinical experience with the single-indicator transpulmonary thermodilution (pulse contour cardiac output, or PiCCO) technique in critically ill medical patients, particularly in those with acute heart failure (AHF). Therefore, we compared the cardiac function of patients with AHF or sepsis using the pulmonary artery catheter (PAC) and the PiCCO technology.
methodsThis retrospective observational study was conducted in the medical intensive care unit of a university hospital. Twelve patients with AHF and nine patients with severe sepsis or septic shock had four simultaneous hemodynamic measurements by PAC and PiCCO during a 24-hour observation period. Comparisons between groups were made with the use of the Mann-Whitney U test. Including all measurements, correlations between data pairs were established using linear regression analysis and are expressed as the square of Pearson's correlation coefficients (r2).
resultsCompared to septic patients, AHF patients had a significantly lower cardiac index, cardiac function index (CFI), global ejection fraction, mixed venous oxygen saturation (SmvO2) and pulmonary vascular permeability index, but higher pulmonary artery occlusion pressure. All patients with a CFI less than 4.5 per minute had an SmvO2 not greater than 70%. In both groups, the CFI correlated with the left ventricular stroke work index (sepsis: r2 = 0.30, P < 0.05; AHF: r2 = 0.23, P < 0.05) and cardiac power (sepsis: r2 = 0.39, P < 0.05; AHF: r2 = 0.45, P < 0.05).
conclusionsIn critically ill medical patients, assessment of cardiac function using transpulmonary thermodilution technique is an alternative to the PAC. A low CFI identifies cardiac dysfunction in both AHF and septic patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.