Trial reportTrials2009
Exercise therapy, quality of life, and activities of daily living in patients with Parkinson disease: a small scale quasi-randomised trial.
Trial report in Trials, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis.The Cochrane database of systematic reviews · 2024Pooled it
- Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis.The Cochrane database of systematic reviews · 2023Pooled it
- Physical Therapist Management of Parkinson Disease: A Clinical Practice Guideline From the American Physical Therapy Association.Physical therapy · 2022Guideline
- Aerobic exercise for Parkinson's disease: a systematic review and meta-analysis of randomized controlled trials.PloS one · 2014Pooled it
- Systematic review of the effectiveness of occupational therapy-related interventions for people with Parkinson's disease.The American journal of occupational therapy : official publication of the American Occupational Therapy AssociationPooled it
- Article
- Importance of Modulating Kynurenic Acid Metabolism-Approaches for the Treatment of Dementia.Biomolecules · 2025Review
- Validity and reliability of the Italian version of the short Parkinson's evaluation scale (SPES/SCOPA).Heliyon · 2024Article
- Inflammation-relevant microbiome signature of the stroke brain, gut, spleen, and thymus and the impact of exercise.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Safety of exercise therapy after acute pulmonary embolism.Phlebology · 2020Article
- Research-based Updates in Swallowing and Communication Dysfunction in Parkinson Disease: Implications for Evaluation and Management.Perspectives of the ASHA special interest groups · 2019Article
- Motor Learning Deficits in Parkinson's Disease (PD) and Their Effect on Training Response in Gait and Balance: A Narrative Review.Frontiers in neurology · 2019Review
- Effects of Non-Pharmacological Treatments on Quality of Life in Parkinson's Disease: A Review.Journal of Parkinson's disease and Alzheimer's disease · 2017Article
- The Effects of Physical Activity in Parkinson's Disease: A Review.Journal of Parkinson's disease · 2016Review
- Turkish Version Study of "Parkinson's Disease Quality of Life Questionnaire" (PDQL).Noro psikiyatri arsivi · 2015Article
- Validation and comparison of 15-D and EQ-5D-5L instruments in a Spanish Parkinson's disease population sample.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014Article
- Quality of life in Parkinson's disease.Journal of medicine and life · 2012Review
- Exercise and motor training in people with Parkinson's disease: a systematic review of participant characteristics, intervention delivery, retention rates, adherence, and adverse events in clinical trials.Parkinson's disease · 2012Article
- A longitudinal study of motor performance and striatal [18F]fluorodopa uptake in Parkinson's disease.Brain imaging and behavior · 2011Article
- Stochastic resonance activity influences serum tryptophan metabolism in healthy human subjects.International journal of tryptophan research : IJTR · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to examine the effect of a 10-week exercise therapy regimen on activities of daily living (ADL) and perceived health status in patients with Parkinson disease.
methodsTwenty-four Parkinson's disease patients entered into the study. Participants were allocated into the experimental (n = 12) or control group (n = 12). ADL was assessed using the Short Parkinson Evaluation Scale/Scale for Outcomes in Parkinson Disease (SPES/SCOPA) and perceived health status was measured using the Parkinson's Disease Quality of Life (PDQL) questionnaire. Patients in the experimental group received pharmacological therapy plus a 1-hour exercise therapy session 4 times a week, while patients in the control group received pharmacological therapy only. The Mann-Whitney U test was used for comparison.
resultsThe mean age of participants was 59.8 (SD = 3.0) and 58.2 (SD = 3.4) years in the experimental and control groups, respectively. The median Hoehn and Yahr stage was 3.0 for both groups. There were no significant differences in all subscales and overall scores between two groups at baseline. However, after the intervention, except for the emotional functioning (P = 0.27), there were significant differences between the two groups for Parkinson symptoms, systemic symptoms, social functioning, and overall scores of the PDQL (all P values < 0.05), and the ADL (P = 0.01) indicating that quality of life was improved in the experimental group.
conclusionThe findings from this small scale quasi-randomised trial showed that exercise therapy was effective in improving activities of daily living and perceived health status in patients with Parkinson's disease. Indeed, exercise therapy could be offered to patients with Parkinson disease, considering that it is low in cost and usually has no negative side effects.
trial registrationCurrent Controlled Trials ISRCTN98825027.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.