Evidence map›Paper›PMID 19669944›Full record

ReviewJournal of molecular neuroscience : MN2010

Nicotine and behavioral sensitization.

Danyan Mao, Daniel S McGehee

Open access · greenAbstract readReview
In one paragraph

Review in Journal of molecular neuroscience : MN, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Nonlinear relationship between CAN current andCognitive neurodynamics · 2022
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Rapid sensitization of physiological, neuronal, and locomotor effects of nicotine: critical role of peripheral drug actions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
  17. Article
  18. Nicotinic regulation of energy homeostasis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2012
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Danyan MaoDepartment of Anesthesia and Critical Care, University of Chicago, MC4028, Chicago, IL 60637, USA.
Daniel S McGehee
University of Chicago · US

Funding

THE UPREGULATION OF NICOTINIC RECEPTORSP01DA019695 · NIDA · UNIVERSITY OF CHICAGO · PI GREEN, WILLIAM · 2007 to 2011
$4.5M
Nicotinic Modulation of the Mesoaccumbens Dopamine SystemR01DA015918 · NIDA · UNIVERSITY OF CHICAGO · PI MCGEHEE, DANIEL S · 2003 to 2007
$1.9M
NIDA NIH HHS DA015918NIDA NIH HHS DA019695NIDA NIH HHS P01 DA019695NIDA NIH HHS R01 DA015918
6 · The paper itself

Abstract

Use of tobacco products contributes to hundreds of thousands of premature deaths and untold millions of dollars in health care costs in this country each year. Nicotine is the principal neuroactive component in tobacco, but, despite ongoing research efforts, the cellular basis of its effects on behavior remains unclear. Efforts to resolve this conundrum have focused on the mesoaccumbens dopamine system, which contributes to the rewarding effects of many addictive drugs, including nicotine. The goal of this review is to outline recent advances and highlight some of the important unanswered questions regarding nicotine's effects on neuronal excitability and synaptic plasticity within the brain reward pathways.

Indexed as

RewardAnimalsBehaviorBrainDopamineHumansNicotineNicotinic AgonistsNucleus AccumbensSynaptic TransmissionTobacco Use DisorderVentral Tegmental AreaDopamineNicotineNicotinic Agonists

Identifiers

PMID19669944
PMCPMC9641718
OpenAlexW2085007471

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.