ArticleHepatology international2008
Spontaneous rupture of metastatic alpha-fetoprotein-producing gastric cancer of the liver.
Article in Hepatology international, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Spontaneous rupture of hepatic metastasis as the initial presentation of gastric hepatoid adenocarcinoma: a rare case report and literature review.Frontiers in oncology · 2026Article
- Alpha-fetoprotein-producing gastric cancer with ruptured liver metastasis mimicking hepatocellular carcinoma.Clinical journal of gastroenterology · 2024Article
- A rare case of ruptured liver metastases from a laryngeal cancer.Radiology case reports · 2021Article
- Intratumoral Hemorrhage of Liver Metastasis from a Rectal Neuroendocrine Tumor.Internal medicine (Tokyo, Japan) · 2019Article
- Spontaneous rupture of hepatic metastasis from small cell neuroendocrine carcinoma of maxillary sinus.World journal of surgical oncology · 2014Article
- Elevated paraneoplastic hypercholesterolemia in a case of hepatoid adenocarcinoma of the stomach with liver metastasis.Clinical journal of gastroenterology · 2013Article
- Alpha-fetoprotein-producing adenocarcinoma in which the metastatic route was determined from calcified lesions.Clinical journal of gastroenterology · 2011Article
Corrections and comments
- Erratum issuedErrata.2008
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An 80-year-old man was admitted to our hospital because of the rupture of the liver. Laboratory data showed iron-deficiency anemia, although there was no liver dysfunction. A computed tomography scan showed large liver tumor with intraperitoneal hemorrhage, and since a serum level of alpha-fetoprotein (AFP) was extremely high, we initially suspected a rupture of hepatocellular carcinoma (HCC). Transarterial embolization was performed to stop bleeding from the tumor, followed by an endoscopic examination that revealed advanced gastric cancer. Histological analysis revealed that both the gastric and the hepatic tumors were moderately to poorly differentiated adenocarcinoma, as well as that both tumors were immunohistochemically positive for AFP. Finally, we diagnosed AFP-producing gastric cancer associated with liver metastasis. Rupture of metastatic liver cancer is rare, and accordingly, distinction from HCC is important, particularly for the cases of AFP-producing gastric cancer.
Identifiers
What OpenQuestion holds
Registered trials
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