ArticleHepatology international2008
The effect of iron depletion on chronic hepatitis C virus infection.
Article in Hepatology international, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases.Hepatology (Baltimore, Md.) · 2011Guideline
- The Role of Red Cell Distribution Width as a Prognostic Marker in Chronic Liver Disease: A Literature Review.International journal of molecular sciences · 2023Review
- Coronavirus disease 2019 (COVID-19) update: From metabolic reprogramming to immunometabolism.Journal of medical virology · 2022Review
- Iron-Induced Hepatocarcinogenesis-Preventive Effects of Nutrients.Frontiers in oncology · 2022Review
- Article
- Hyperferritinemia-A Clinical Overview.Journal of clinical medicine · 2021Review
- Iron at the Interface of Hepatocellular Carcinoma.International journal of molecular sciences · 2021Review
- When should iron supplementation in dialysis patients be avoided, minimized or withdrawn?Seminars in dialysis · 2019Article
- Post-transfusion hepatitis C virus infection among β-thalassaemic individuals with associated clinical parameters.The Indian journal of medical research · 2018Article
- Normalizing serum hepcidin but not α-1-antitrypsin level during effective treatment of chronic hepatitis C.Clinical and experimental hepatology · 2017Article
- Hepcidin/ferroportin expression levels involve efficacy of pegylated-interferon plus ribavirin in hepatitis C virus-infected liver.World journal of gastroenterology · 2015Article
- Abnormal serum iron markers in chronic hepatitis B virus infection may be because of liver injury.European journal of gastroenterology & hepatology · 2015Article
- Serum transferrin as a liver fibrosis biomarker in patients with chronic hepatitis B.Clinical and molecular hepatology · 2014Article
- Quantification of liver iron with MRI: state of the art and remaining challenges.Journal of magnetic resonance imaging : JMRI · 2014Review
- Association between inherited monogenic liver disorders and chronic hepatitis C.World journal of hepatology · 2014Article
- Improved Serum Alpha-Fetoprotein Levels after Iron Reduction Therapy in HCV Patients.ISRN hepatology · 2014Article
- Serum iron markers in patients with chronic hepatitis C infection.Hepatitis monthly · 2013Article
- Low dose ribavirin for treatment of hepatitis C virus infected thalassemia major patients; new indications for combination therapy.Hepatitis monthly · 2012Article
- Article
- A novel monoclonal antibody immunoassay for the detection of human serum hepcidin.Journal of gastroenterology · 2011Article
Corrections and comments
- Erratum issuedErrata.2008
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing evidence exists that iron overload, a common finding in chronic hepatitis C virus (HCV) infection, plays an important role in the pathophysiology of this disease. The mechanisms by which iron excess induces liver damage along with the benefit of iron depletion via phlebotomy on biochemical and histological outcomes in patients with chronic HCV infection have been discussed in this review. Finally, we focus on the effect of iron reduction on the rate of response to interferon antiviral therapy.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.