ArticleJournal of hematopathology2008
Translocation detection in lymphoma diagnosis by split-signal FISH: a standardised approach.
Article in Journal of hematopathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 29 citations in OpenAlex.
- Current understanding of the role and regulation of miRNAs in Burkitt lymphoma.Blood and lymphatic cancer : targets and therapy · 2018Review
- Validation of break-apart and fusion MYC probes using a digital fluorescence in situ hybridization capture and imaging system.Journal of pathology informatics · 2016Article
- Burkitt lymphoma beyond MYC translocation: N-MYC and DNA methyltransferases dysregulation.BMC cancer · 2015Article
- Article
- Nijmegen breakage syndrome (NBS).Orphanet journal of rare diseases · 2012Review
- Article
- IG/MYC rearrangements are the main cytogenetic alteration in plasmablastic lymphomas.The American journal of surgical pathology · 2010Article
- Double-staining chromogenic in situ hybridization as a useful alternative to split-signal fluorescence in situ hybridization in lymphoma diagnostics.Haematologica · 2010Article
- New developments in the pathology of malignant lymphoma: a review of the literature published from August to December 2008.Journal of hematopathology · 2009Article
Corrections and comments
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Authors and funding
21 authors at 12 institutions in 11 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lymphomas originating from the lymphatic system comprise about 30 entities classified according to the World Health Organization (WHO). The histopathological diagnosis is generally considered difficult and prone to mistakes. Since non-random chromosomal translocations are specifically involved in different lymphoma entities, their detection will be increasingly important. Hence, a split-signal fluorescence in situ hybridisation (FISH) procedure would be helpful in discriminating the most difficult classifications. The Euro-FISH programme, a concerted action of nine European laboratories, has validated a robust, standardised protocol to improve the diagnostic approach on lymphoma entities. Therefore, 16 fluorescent probes and 10 WHO entities, supplemented with reactive cases, were selected. The results of the Euro-FISH programme show that all probes were correctly cytogenetically located, that the standardised protocol is robust, resulting in reliable results in approximately 90% of cases, and that the procedure could be implemented in every laboratory, bringing the relatively easy interpretation of split-signal probes within the reach of many pathology laboratories.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.