ArticleClinical ophthalmology (Auckland, N.Z.)2007
Differential diagnosis of leukocoria and strabismus, first presenting signs of retinoblastoma.
Article in Clinical ophthalmology (Auckland, N.Z.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 63 citations in OpenAlex.
- Ocular Toxocariasis Mimicking Persistent Fetal Vasculature in a Child.Journal of vitreoretinal diseases · 2026Article
- Smartphone applications for early screening of retinoblastoma: a scoping review.BMC ophthalmology · 2026Article
- Patterns and temporal trends in childhood cancer incidence in northern Ghana: evidence from medical records, 2016 to 2023.BMC pediatrics · 2025Article
- Retinocytoma: understanding pathogenesis, diagnosis, and treatment approaches.International journal of retina and vitreous · 2025Review
- Biosynthesis of sulfur quantum dots and cerium oxide nanoparticles for bioimaging and reactive oxygen species modulation in Y79 retinoblastoma cancer cells.BioImpacts : BI · 2025Article
- Retinoblastoma: An update on genetic origin, classification, conventional to next-generation treatment strategies.Heliyon · 2024Review
- [Embryonic development and congenital diseases of the orbit].Radiologie (Heidelberg, Germany) · 2024Review
- Leukocoria in a 4-year-old boy.Digital journal of ophthalmology : DJO · 2024Article
- Conservative treatment using laser diode and systemic chemotherapy for early-stage bilateral retinoblastoma: A 14-year prospective cohort study.Cancer reports (Hoboken, N.J.) · 2024Article
- Nanoparticle-based delivery systems as emerging therapy in retinoblastoma: recent advances, challenges and prospects.Nanoscale advances · 2023Review
- Seasonality of main childhood embryonal tumours and rhabdomyosarcoma, France, 2000-2015.Cancer medicine · 2023Article
- Early detection of visual impairment in young children using a smartphone-based deep learning system.Nature medicine · 2023Article
- Improving Medical Students' Awareness About Retinoblastoma: A Practical Strategy.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Hyperoleon masquerading as leukocoria.BMJ case reports · 2021Article
- Evaluation of the red reflex: An overview for the pediatrician.World journal of methodology · 2021Article
- Article
- Multi-Functionalized Nanomaterials and Nanoparticles for Diagnosis and Treatment of Retinoblastoma.Biosensors · 2021Review
- Spotlight on the pediatric eye: a pictorial review of orbital anatomy and congenital orbital pathologies.The neuroradiology journal · 2021Review
- Unilateral Leukocoria in an Infant.Cureus · 2020Article
- Long-Term Clinical Results and Management following Vitrectomy in Undetected Retinoblastoma Eyes.Ocular oncology and pathology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leukocoria in infants is always a danger signal as retinoblastoma, a malignant retinal tumor, is responsible for half of the cases in this age group. More common signs should also be considered suspicious until proved otherwise, such as strabismus, the second most frequent sign of retinoblastoma. Less frequent manifestations are inflammatory conditions resistant to treatment, hypopyon, orbital cellulitis, hyphema or heterochromia. Other causal pathologies, including persistent hyperplastic primary vitreous (PHPV), Coats' disease, ocular toxocariasis or retinopathy of prematurity, may also manifest the same warning signs and require specialized differential diagnosis. Members of the immediate family circle are most likely to notice the first signs, the general practitioner, pediatrician or general ophthalmologist the first to be consulted. On their attitude will depend the final outcome of this vision and life-threatening disease. Early diagnosis is vital.
Indexed as
Identifiers
19668520PMC2704541W1881461461What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.