ReviewNature reviews. Urology2009
Diagnosis and management of vesicoureteral reflux in children.
Review in Nature reviews. Urology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 55 citations in OpenAlex.
- Does vesicoureteral reflux severity impact breakthrough UTI risk: a multi-institutional analysis and risk stratification.World journal of urology · 2026Article
- Primary vesicoureteral reflux.Nature reviews. Disease primers · 2024Review
- The Utility of Noninvasive Urinary Biomarkers for the Evaluation of Vesicoureteral Reflux in Children.International journal of molecular sciences · 2023Article
- A quantitative analysis of voiding cystourethrogram features confirms the association between high-grade vesicoureteral reflux with male sex, younger age, and hydronephrosis.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023Article
- Management of Vesicoureteral Reflux: What Have We Learned Over the Last 20 Years?Frontiers in pediatrics · 2021Review
- Association of Genetic Polymorphisms inIranian journal of public health · 2020Article
- Transplantation of mature adipocyte-derived dedifferentiated fat cells for the treatment of vesicoureteral reflux in a rat model.International urology and nephrology · 2016Article
- Genetics of Vesicoureteral Reflux.Current genomics · 2016Article
- Detecting reflux: does ureteric jet Doppler waveform have a role?Pediatric nephrology (Berlin, Germany) · 2013Article
- Diagnostic accuracy of magnetic resonance voiding cystourethrography for detecting vesico-ureteral reflux in children and adolescents.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013Article
- The impact of vesicoureteral reflux treatment on the incidence of urinary tract infection.Pediatric nephrology (Berlin, Germany) · 2012Review
- Concomitant vesicoureteral reflux and gastroesophageal reflux: an analytic cross-sectional study.International urology and nephrology · 2012Article
- Efficacy of hydrodistention implantation technique in treating high-grade vesicoureteral reflux.Korean journal of urology · 2012Article
- Genetics of vesicoureteral reflux.Nature reviews. Urology · 2011Review
- Assessing vesicoureteral reflux in live inbred mice via ultrasound with a microbubble contrast agent.American journal of physiology. Renal physiology · 2011Article
- Demographic features and antibiotic resistance among children hospitalized for urinary tract infection in northwest Iran.Infection and drug resistance · 2011Article
- Medical versus surgical management for vesicoureteric reflux: the case for medical management.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2010Article
- Genetic discovery in vesicoureteral reflux using exome sequencing: A pilot study.Medical journal, Armed Forces IndiaArticle
- Bladder Dysfunction in Children with Primary Vesicoureteral Reflux: Do We Need to Change Indications for Surgery?Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Critical evaluation of previously accepted dogma regarding the evaluation and treatment of vesicoureteral reflux (VUR) has raised significant questions regarding all aspects of VUR management. Whereas the standard of care previously consisted of antibiotic prophylaxis for any child with VUR, it is now unclear which children, if any, truly benefit from antibiotic prophylaxis. Operative intervention for VUR constitutes overtreatment in many children, yet there are limited data available to indicate which children benefit from VUR correction through decreased rates of adverse long-term clinical sequelae. Studies with longer follow-up demonstrate decreased efficacy of endoscopic therapy that was previously hoped to approach the success of ureteroneocystostomy. Prospective studies might identify risk factors for pyelonephritis and renal scarring without antibiotic prophylaxis. Careful retrospective reviews of adults with a history of reflux might allow childhood risk factors for adverse sequelae to be characterized. Through analysis of multiple characteristics, better clinical management of VUR on an individualized basis will become the new standard of care.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.