ReviewNature reviews. Neurology2009
Reducing prehospital delay in acute stroke.
Review in Nature reviews. Neurology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Investigation of Public Awareness of Core Stroke Symptoms
Stroke Awareness and Help-seeking Behaviour: Predictors for Prehospital Delay in Stroke Treatment
Who cites it
47 citing papers in PubMed.
- Effect of a comprehensive health education program on pre-hospital delay intentions in high-risk stroke population and caregivers.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017Trial
- Geographic Disparities in Stroke Action Awareness in China: A National Survey.CNS neuroscience & therapeutics · 2026Article
- Insights Into Remote Ischemic Conditioning miRNA Effects on Brain Endothelial Cells During Ischemia-Reperfusion.Microcirculation (New York, N.Y. : 1994) · 2026Article
- The economic impacts of the multifaceted stroke 1-2-0 educational campaign in China.BMC health services research · 2026Article
- Factors associated with missed stroke diagnosis in prehospital triage: a single-center cohort study.BMC neurology · 2026Article
- Race- and Ethnicity-Specific Hospital Arrival and Emergency Medicine Service Activation Times by US State for Ischemic Stroke.Journal of the American Heart Association · 2026Article
- CFAST: a simplified and culturally adapted stroke education tool for Chinese communities.Frontiers in stroke · 2026Article
- Emergency Medical Service Responses for Older Adults: A Retrospective Observational Study Comparing Nursing Homes and the Community.Healthcare (Basel, Switzerland) · 2025Article
- Analysis of prehospital delay in acute ischaemic stroke and its influencing factors: a multicentre prospective case registry study in China.Stroke and vascular neurology · 2025Article
- Prehospital stroke care in low- and middle-income countries: A World Stroke Organization (WSO) scientific statement.International journal of stroke : official journal of the International Stroke Society · 2025Review
- Stroke knowledge and attitudes influence early hospital arrival in acute ischemic stroke: a multicenter cross-sectional survey from Hubei Province, China.Frontiers in neurology · 2025Article
- Characterizing TIA and stroke symptomatology in a population-based study: implications for and diagnostic value of FAST-based public education.BMC public health · 2024Article
- Prehospital neurological emergencies- a survey on the state of prehospital neurological assessment by emergency medical professionals.BMC emergency medicine · 2024Article
- A Review of emergency medical services for stroke.African health sciences · 2024Review
- Therapeutic management of ischemic stroke.Naunyn-Schmiedeberg's archives of pharmacology · 2024Review
- Trends in Stroke Thrombolysis Care Metrics and Outcomes by Race and Ethnicity, 2003-2021.JAMA network open · 2024Article
- Recognition of visual symptoms in stroke: a challenge to patients, bystanders, and Emergency Medical Services.BMC emergency medicine · 2023Article
- Characteristics of Early Presenters after Intracerebral Hemorrhage.Journal of stroke · 2022Article
- Analysis of Time to the Hospital and Ambulance Use Following a Stroke Community Education Intervention in China.JAMA network open · 2022Article
- Interactive Training of the Emergency Medical Services Improved Prehospital Stroke Recognition and Transport Time.Frontiers in neurology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the proven benefits of thrombolysis for patients presenting with acute ischemic stroke, only a limited number of patients receive thrombolytic therapy. The reason for the low treatment rate is that thrombolysis is only effective a few hours after the onset of ischemic stroke, so delays in patients being admitted to hospital and being diagnosed mean that the therapeutic window is often missed. Major factors that lead to prehospital delay include the general public's lack of knowledge of stroke symptoms and their poor understanding of the appropriate course of action following a stroke. Indeed, the patients who arrive early in hospital tend to be those who recognize the symptoms of stroke and take them seriously. Deficiencies in the identification of stroke by emergency medical services and general practitioners also contribute to prehospital delay. Aggressive, combined educational programs aimed at the general public, general practitioners, and medical and paramedical hospital staff can lead to increased stroke treatment rates. In this Review, we explore the extent of prehospital delay in stroke, identify the factors that affect the time taken for patients to reach hospital, and describe strategies designed to reduce the delay.
Indexed as
Identifiers
19668246What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.