ReviewBehavioural pharmacology2009
Effects of chronic administration of drugs of abuse on impulsive choice (delay discounting) in animal models.
Review in Behavioural pharmacology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 91 citations in OpenAlex.
- The mesocorticolimbic system in stimulant use disorder.Molecular psychiatry · 2025Review
- Effects of methamphetamine on delay discounting in rats using concurrent chains.Learning & behavior · 2025Review
- Healthy aging in rats is associated with a decline in the ability to inhibit maladaptive responses, but not in measures of self-control by delayed gratification.Frontiers in aging neuroscience · 2025Article
- Divergent risky decision-making and impulsivity behaviors in Lewis rat substrains with low genetic difference.Behavioral neuroscience · 2023Article
- Age differences in the behavioural economics of cannabis use: Do adolescents and adults differ on demand for cannabis and discounting of future reward?Drug and alcohol dependence · 2022Article
- Increased Risky Choice and ReducedInternational journal of molecular sciences · 2022Article
- Evaluating effects of episodic future thinking on valuation of delayed reward in cocaine use disorder: a pilot study.The American journal of drug and alcohol abuse · 2021Article
- Effects of substance misuse on reward-processing in patients with attention-deficit/hyperactivity disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- Reducing impulsive choice VII: effects of duration of delay-exposure training.Animal cognition · 2021Article
- Delay and probability discounting in cocaine use disorder: Comprehensive examination of money, cocaine, and health outcomes using gains and losses at multiple magnitudes.Experimental and clinical psychopharmacology · 2020Article
- Effects of opioid/cannabinoid mixtures on impulsivity and memory in rhesus monkeys.Behavioural pharmacology · 2020Article
- Prior cocaine self-administration impairs attention signals in anterior cingulate cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Article
- Effects of Substance Misuse and Family History of Substance Use Disorder on Delay Discounting in Adolescents and Young Adults with Attention-Deficit/Hyperactivity Disorder.European addiction research · 2020Article
- Repeated administration of synthetic cathinone 3,4-methylenedioxypyrovalerone persistently increases impulsive choice in rats.Behavioural pharmacology · 2019Article
- Genomic basis of delayed reward discounting.Behavioural processes · 2019Review
- Genetic influences on delayed reward discounting: A genome-wide prioritized subset approach.Experimental and clinical psychopharmacology · 2019Article
- Previous cocaine self-administration disrupts reward expectancy encoding in ventral striatum.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Article
- Early life adversity and health-risk behaviors: proposed psychological and neural mechanisms.Annals of the New York Academy of Sciences · 2018Review
- Effects of morphine/CP55940 mixtures on an impulsive choice task in rhesus monkeys.Behavioural pharmacology · 2018Article
- Age and impulsive behavior in drug addiction: A review of past research and future directions.Pharmacology, biochemistry, and behavior · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Drug-addicted individuals show high levels of impulsive choice, characterized by preference for small immediate over larger but delayed rewards. Although the causal relationship between chronic drug use and elevated impulsive choice in humans has been unclear, a small but growing body of literature over the past decade has shown that chronic drug administration in animal models can cause increases in impulsive choice, suggesting that a similar causal relationship may exist in human drug users. This article reviews this literature, with a particular focus on the effects of chronic cocaine administration, which have been most thoroughly characterized. The potential mechanisms of these effects are described in terms of drug-induced neural alterations in ventral striatal and prefrontal cortical brain systems. Some implications of this research for pharmacological treatment of drug-induced increases in impulsive choice are discussed, along with suggestions for future research in this area.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.