ArticleBioorganic & medicinal chemistry letters2009
Addressing the malaria drug resistance challenge using flow cytometry to discover new antimalarials.
Article in Bioorganic & medicinal chemistry letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Cholesterol-dependent enrichment of understudied erythrocytic stages of human Plasmodium parasites.Scientific reports · 2020Article
- Growth of Plasmodium falciparum in response to a rotating magnetic field.Malaria journal · 2018Article
- Antimalarial Activity of Acetylenic Thiophenes from Echinops hoehnelii Schweinf.Molecules (Basel, Switzerland) · 2017Article
- Synthesis of 2,1-benzisoxazole-3(1H)-ones by base-mediated photochemical N-O bond-forming cyclization of 2-azidobenzoic acids.Beilstein journal of organic chemistry · 2016Article
- Myristicyclins A and B: antimalarial procyanidins from Horsfieldia spicata from Papua New Guinea.Organic letters · 2014Article
- 3-bromohomofascaplysin A, a fascaplysin analogue from a Fijian Didemnum sp. ascidian.Bioorganic & medicinal chemistry · 2011Article
- Expanding the Antimalarial Drug Arsenal-Now, But How?Pharmaceuticals (Basel, Switzerland) · 2011Article
- Simple flow cytometric detection of haemozoin containing leukocytes and erythrocytes for research on diagnosis, immunology and drug sensitivity testing.Malaria journal · 2011Article
- Methodology and application of flow cytometry for investigation of human malaria parasites.Journal of immunological methods · 2011Review
- An adaptable two-color flow cytometric assay to quantitate the invasion of erythrocytes by Plasmodium falciparum parasites.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2010Article
- A comparative study of a flow-cytometry-based assessment of in vitro Plasmodium falciparum drug sensitivity.Malaria journal · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
A new flow cytometry method that uses an optimized DNA and RNA staining strategy to monitor the growth and development of the Plasmodium falciparum strain W2mef has been used in a pilot study and has identified Bay 43-9006 1, SU 11274 2, and TMC 125 5 as compounds that exhibit potent (<1 microM) overall and ring stage in vitro antimalarial activity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.