Evidence map›Paper›PMID 19664218›Full record

ReviewBMC medicine2009

Management and prevention of chronic obstructive pulmonary disease exacerbations: a state of the art review.

John R Hurst, Jadwiga A Wedzicha

Abstract readReview
In one paragraph

Review in BMC medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Impact of a functional polymorphism in the PAR-1 gene promoter in COPD and COPD exacerbations.American journal of physiology. Lung cellular and molecular physiology · 2014
    Article
  10. Article
  11. Article
  12. Chronic obstructive pulmonary disease.Lancet (London, England) · 2012
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Roflumilast.Nature reviews. Drug discovery · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John R HurstAcademic Unit of Respiratory Medicine, Royal Free Campus, UCL Medical School, London, UK. j.hurst@medsch.ucl.ac.uk
Jadwiga A Wedzicha

Funding

Medical Research Council G0800570
6 · The paper itself

Abstract

Exacerbations of chronic obstructive pulmonary disease (COPD) are important events in the natural history of this prevalent and devastating condition. This review provides a concise, state of the art summary on prevention and management of exacerbations. Considerable new data underpins evidence in support of many preventative interventions, pharmacological and non-pharmacological, that are now available. Challenges remain in developing new approaches, and delivering those that already exist to the right patient at the right time. Management of an exacerbation remains stepwise according to clinical severity, but there is now additional focus on addressing comorbidities and taking the opportunity at acute events to optimise preventative strategies for the future. Ultimately, exacerbations are heterogeneous events in a heterogeneous disease, and an individualised approach is paramount.

Indexed as

Case ManagementSecondary PreventionHumansPulmonary Disease, Chronic ObstructiveReview Literature as Topic

Identifiers

PMID19664218
PMCPMC2734841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.