ReviewPharmacoEconomics2009
Societal and patient burden of fibromyalgia syndrome.
Review in PharmacoEconomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06226376 (The Effects of EXOPULSE Mollii Suit on Fibromyalgia Syndrome in Patients With Fibromyalgia), which is not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of EXOPULSE Mollii Suit on Fibromyalgia Syndrome in Patients With Fibromyalgia (EXOFIB 2): A Sham Controlled Randomized Double-Blind Trial
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Optimal aerobic exercise dose for pain relief in fibromyalgia syndrome: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- The potential impact of exercise on affect and neuroinflammation in older adults living with fibromyalgia: a scoping review.Frontiers in human neuroscience · 2024Pooled it
- 2012 Canadian Guidelines for the diagnosis and management of fibromyalgia syndrome: executive summary.Pain research & managementGuideline
- The effects of EXOPULSE Mollii Suit in patients with fibromyalgia: a double-blind randomized sham-controlled trial (EXOFIB2).Pain medicine (Malden, Mass.) · 2026Trial
- Randomized Controlled Trial of Acupuncture for Women with Fibromyalgia: Group Acupuncture with Traditional Chinese Medicine Diagnosis-Based Point Selection.Pain medicine (Malden, Mass.) · 2018Trial
- Decrease of fear avoidance beliefs following person-centered progressive resistance exercise contributes to reduced pain disability in women with fibromyalgia: secondary exploratory analyses from a randomized controlled trial.Arthritis research & therapy · 2016Trial
- Resource utilisation and direct costs in patients with recently diagnosed fibromyalgia who are offered one of three different interventions in a randomised pragmatic trial.Clinical rheumatology · 2016Trial
- Resistance exercise improves muscle strength, health status and pain intensity in fibromyalgia--a randomized controlled trial.Arthritis research & therapy · 2015Trial
- Virtual reality exposure therapy as treatment for pain catastrophizing in fibromyalgia patients: proof-of-concept study (Study Protocol).BMC musculoskeletal disorders · 2011Trial
- A Brief Mindfulness Intervention for Pain Management in Fibromyalgia: A Single-arm Open-Label Study.Restorative neurology and neuroscience · 2026Article
- Article
- The influence of social support on pain, symptom severity, and quality of life in fibromyalgia.Turkish journal of physical medicine and rehabilitation · 2026Article
- FiRST Screening Positivity Among Patients Attending a Tertiary Chronic Pain service in Oman.Journal of pain research · 2026Article
- Effectiveness of Transcranial Direct Current Stimulation (tDCS) during a Virtual Reality Task in Women with Fibromyalgia-A Randomized Clinical Study.Brain sciences · 2024Article
- Exploring Pain Reduction through Physical Activity: A Case Study of Seven Fibromyalgia Patients.Bioengineering (Basel, Switzerland) · 2024Article
- Social costs associated with fibromyalgia in Spain.Health economics review · 2024Article
- A behavioral and brain imaging dataset with focus on emotion regulation of women with fibromyalgia.Scientific data · 2022Article
- Is Whole-Body Cryostimulation an Effective Add-On Treatment in Individuals with Fibromyalgia and Obesity? A Randomized Controlled Clinical Trial.Journal of clinical medicine · 2022Article
- Patient Perspectives of Disease Activity, Medications and Substance Use in People with Fibromyalgia.Open access rheumatology : research and reviews · 2022Article
- The Impact of a Peer Social Support Network from the Perspective of Women with Fibromyalgia: A Qualitative Study.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibromyalgia syndrome (FMS) is an under-diagnosed disorder of unknown aetiology, characterized by chronic widespread muscular pain, often accompanied by somatic and psychological symptoms. Several studies have described the impact of FMS on patients' functionality, disability and quality of life. Other studies have reported on the burden to patients, healthcare payers and society. This review brings the existing evidence together and concludes that the patient burden of fibromyalgia is very high in comparison with many other conditions. The burden to healthcare payers and society is important as well, and can be mostly explained by factors not directly related to the treatment of FMS. Data suggest that the cost before diagnosis may even be higher than the cost after diagnosis. It is very likely that the combination of symptoms not only complicates the recognition and treatment of FMS, but also magnifies the burden of FMS. Despite the complex and controversial construct of this syndrome, the results in terms of patient, healthcare payer and societal burden are quite consistent.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.