Evidence map›Paper›PMID 19662416›Full record

ReviewCurrent genetics2009

Biology and genetics of the pathogenic yeast Candida parapsilosis.

Jozef Nosek, Zuzana Holesova, Peter Kosa, Attila Gacser, Lubomir Tomaska

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Comparative Evaluation ofBiomedicines · 2024
    Article
  3. Synthesis of TiONanomaterials (Basel, Switzerland) · 2023
    Article
  4. Culture media influencesFrontiers in cellular and infection microbiology · 2023
    Article
  5. Article
  6. Contemporary comparison of infective endocarditis caused by Candida albicans and Candida parapsilosis: a cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Article
  7. Article
  8. Article
  9. AJournal of fungi (Basel, Switzerland) · 2021
    Article
  10. Journal of fungi (Basel, Switzerland) · 2021
    Article
  11. Article
  12. Candida parapsilosis: from Genes to the Bedside.Clinical microbiology reviews · 2019
    Review
  13. Article
  14. An Azole-ResistantFrontiers in microbiology · 2018
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jozef NosekDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University, Mlynska dolina CH-1, 842 15, Bratislava, Slovak Republic. nosek@fns.uniba.sk
Zuzana Holesova
Peter Kosa
Attila Gacser
Lubomir Tomaska
Comenius University Bratislava · SKUniversity of Szeged · HU

Funding

Studies of Telomere Structure Using Yeast Model SystemsR03TW005654 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GRIFFITH, JACK D · 2001 to 2008
$227k
FIC NIH HHS 2-R03-TW005654-04A1Howard Hughes Medical Institute 55005622
6 · The paper itself

Abstract

The yeast Candida parapsilosis is an opportunistic human pathogen frequently associated with nosocomial infections in neonates and patients with diminished immunity. A growing number of studies powered by recent advances in molecular genetics and genomics provide a background for uncovering the molecular basis of its virulence that suggests promising avenues for therapeutic intervention against this pathogen. Importantly, these studies also revealed several unique genetic and physiological features absent in model organisms, such as baker's and fission yeasts. Hence, besides the clinical impact, C. parapsilosis represents an interesting non-conventional model suitable for investigations of several fundamental biological phenomena in cellular physiology, morphogenesis, and genome maintenance. In this study, we provide a concise review on C. parapsilosis biology and highlight its interesting biological features. In addition, we summarize approaches for genetic manipulation, which have enhanced research on this species by overcoming limitations of conventional genetic analysis caused primarily by an apparent absence of a sexual cycle and the diploid state of its genome.

Indexed as

CandidaChromosomes, FungalGenome, FungalMorphogenesisPhylogeny

Identifiers

PMID19662416
OpenAlexW2146978337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.