ArticleObesity (Silver Spring, Md.)2010
Fat distribution, aerobic fitness, blood lipids, and insulin sensitivity in African-American and European-American women.
Article in Obesity (Silver Spring, Md.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 66 citations in OpenAlex.
- Alterations in Hemoglobin and Serum 25-hydroxyvitamin D are Related Before and After Weight Loss Independent of African Admixture.International journal of sport nutrition and exercise metabolism · 2017Trial
- Modulation of the lipidomic profile due to a lipid challenge and fitness level: a postprandial study.Lipids in health and disease · 2015Trial
- Article
- The Association of Upper Body Obesity with Insulin Resistance in the Newfoundland Population.International journal of environmental research and public health · 2021Article
- Article
- Comparative Cardiorespiratory Fitness in Children: Racial Disparity May Begin Early in Childhood.Pediatric cardiology · 2019Article
- Article
- Differences in Glucose Metabolism Among Women With Spinal Cord Injury May Not Be Fully Explained by Variations in Body Composition.Archives of physical medicine and rehabilitation · 2019Article
- Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans.Obesity (Silver Spring, Md.) · 2019Article
- Central fat accretion and insulin sensitivity: differential relationships in parous and nulliparous women.International journal of obesity (2005) · 2017Article
- Examining the prevalence of metabolic syndrome among overweight/obese African-American breast cancer survivors vs. matched non-cancer controls.Journal of cancer survivorship : research and practice · 2017Article
- Triglyceride glucose-waist circumference, a novel and effective predictor of diabetes in first-degree relatives of type 2 diabetes patients: cross-sectional and prospective cohort study.Journal of translational medicine · 2016Article
- Black and White race differences in aerobic capacity, muscle fiber type, and their influence on metabolic processes.Sports medicine (Auckland, N.Z.) · 2015Review
- Ethnic differences in associations between fat deposition and incident diabetes and underlying mechanisms: the SABRE study.Obesity (Silver Spring, Md.) · 2015Article
- Uncovering physiological mechanisms for health disparities in type 2 diabetes.Ethnicity & disease · 2015Review
- Specific characterization of regional storage fat in upper and lower limbs of young healthy adults.SpringerPlus · 2015Article
- The application of visceral adiposity index in identifying type 2 diabetes risks based on a prospective cohort in China.Lipids in health and disease · 2014Article
- Association between Appendicular Fat Mass and Metabolic Risk Factors.Korean journal of family medicine · 2014Article
- Low cardiorespiratory fitness in African Americans: a health disparity risk factor?Sports medicine (Auckland, N.Z.) · 2013Review
- Effects of age and aerobic fitness on myocardial lipid content.Circulation. Cardiovascular imaging · 2013Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The purpose of this study was to determine independent relationships of intra-abdominal adipose tissue (IAAT), leg fat, and aerobic fitness with blood lipids and insulin sensitivity (S(i)) in European-American (EA) and African-American (AA) premenopausal women. Ninety-three EA and ninety-four AA with BMI between 27 and 30 kg/m(2) had IAAT by computed tomography, total fat and leg fat by dual-energy X-ray absorptiometry, aerobic fitness by a graded exercise test, African admixture (AFADM) by ancestry informative markers, blood lipids by the Ektachem DT system, and S(i) by glucose tolerance test. Independent of age, aerobic fitness, AFADM, and leg fat, IAAT was positively related to low-density lipoprotein-cholesterol (LDL-C), cholesterol-high-density lipoprotein (HDL) ratio, triglycerides (TGs), and fasting insulin (standardized beta varying 0.16-0.34) and negatively related to HDL-cholesterol (HDL-C) and S(i) (standardized beta -0.15 and -0.25, respectively). In contrast, independent of age, aerobic fitness, AFADM, and IAAT, leg fat was negatively related to total cholesterol, LDL-C, cholesterol-HDL ratio, TGs, and fasting insulin (standardized beta varying -0.15 to -0.21) and positively related to HDL-C and S(i) (standardized beta 0.16 and 0.23). Age was not independently related to worsening of any blood lipid but was related to increased S(i) (standardized beta for S(i) 0.25, insulin -0.31). With the exception of total cholesterol and LDL-C, aerobic fitness was independently related to worsened blood lipid profile and increased S(i) (standardized beta varying 0.17 to -0.21). Maintenance of favorable fat distribution and aerobic fitness may be important strategies for healthy aging, at least in premenopausal EA and AA women.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.