ArticleScience (New York, N.Y.)2009
Folding DNA into twisted and curved nanoscale shapes.
Article in Science (New York, N.Y.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 397 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
397 citing papers in PubMed.
- pH-Driven Actuation of Unmodified DNA Origami Rectangles.Angewandte Chemie (International ed. in English) · 2026Article
- Tetrahedral DNA Nanostructures: A Structural-Family-Aware Review from Computational Design and Biological Stability to Translational Nanomedicine.Nanomaterials (Basel, Switzerland) · 2026Review
- Controlling membrane tension by dynamic DNA nanorings.bioRxiv : the preprint server for biology · 2026Article
- Expandable DNA-origami rings as a nanomechanical platform for studying disordered nucleoporins.bioRxiv : the preprint server for biology · 2026Article
- The Ion Permeability of DNA Nanotube Channels.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- DNA origami-based drug delivery and cell manipulation: toward intelligent nanomedicine.RSC chemical biology · 2026Review
- DNA-Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- From Blueprint to Breakthrough: How Far Can We Fold DNA Origami for Nano-Enabled Technologies?JACS Au · 2026Review
- A multiple-encrypted DNA device for secure communication.Science advances · 2026Article
- Suppression of Aggregation Enhances Placement Fidelity of Asymmetrical Right Triangle DNA Origami.JACS Au · 2026Article
- Bioproduction of ∼10 knt single-stranded DNA for constructing large DNA origami structures.Materials today. Bio · 2026Article
- Dynamic DNA Nanomachines for Biosensing and Drug Delivery.Sensors (Basel, Switzerland) · 2026Review
- Classifying Multistate DNA Origami: An Automated Approach with Minimal Labeling and Confidence-Based Filtering.Journal of chemical information and modeling · 2026Article
- De novo design of DNA origami with a generative diffusion model.Nature communications · 2026Article
- DNA Helix Bundle-Encoded Multi-Bit Information Readout by Sapphire-Supported Nanopores.Advanced functional materials · 2026Article
- DNA Nanostructure-Assembled Metallic Nanoparticles for Biosensing Applications.Molecules (Basel, Switzerland) · 2026Review
- Omega Nucleic Acids (ΩNA), Ultimate Nucleic Acids for Future Technology.Molecules (Basel, Switzerland) · 2026Review
- A blueprint for curved matter: The art of kirigami in 3D self-assembly.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Nanorobots: Trailblazing the Future of Pharmaceuticals Through Targeted Therapy and Disease Monitoring.Recent advances in drug delivery and formulation · 2026Review
- Designer RNA nanostructures co-transcribed and self-assembled inside human cell nuclei.Nature communications · 2025Article
337 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
We demonstrate the ability to engineer complex shapes that twist and curve at the nanoscale from DNA. Through programmable self-assembly, strands of DNA are directed to form a custom-shaped bundle of tightly cross-linked double helices, arrayed in parallel to their helical axes. Targeted insertions and deletions of base pairs cause the DNA bundles to develop twist of either handedness or to curve. The degree of curvature could be quantitatively controlled, and a radius of curvature as tight as 6 nanometers was achieved. We also combined multiple curved elements to build several different types of intricate nanostructures, such as a wireframe beach ball or square-toothed gears.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.